1-methyl-2-pyrrolidone (nmp): reproductive and developmental toxicity study by inhalation in the rat

ABSTRACT A two-generation reproduction study with a developmental toxicity component was conducted. For the reproduction phase, male and female rats inhaled 0, 10, 51, or 116 ppm NMP daily for 6 hr/day, 7 days/week from 34 days of age to the end of the mating period for the males (100 exposure days)...

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Veröffentlicht in:	Drug and chemical toxicology (New York, N.Y. 1978) N.Y. 1978), 1995-01, Vol.18 (4), p.271-293
Hauptverfasser:	Solomon, H. M., Burgess, B. A., Kennedy, G. L., Staples, R. E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Analysis of Variance Animals Biological and medical sciences Body Weight - drug effects Embryology: invertebrates and vertebrates. Teratology Embryonic and Fetal Development - drug effects Female Fertility - drug effects Fundamental and applied biological sciences. Psychology Gestational Age Lactation - drug effects Litter Size - drug effects Male Pregnancy Prenatal Exposure Delayed Effects Pyrrolidinones - administration & dosage Pyrrolidinones - toxicity Random Allocation Rats Reproduction - drug effects Sex Factors Teratogens - toxicity Teratology. Teratogens
Online-Zugang:	Volltext
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