Variation in the expression of p53, c-myc, and bcl-2 oncoproteins in individual patient cultures of normal urothelium exposed to cobalt 60 gamma-rays and N-nitrosodiethanolamine

The controls determining the initial response of cells to DNA damage probably determine whether a cancer will ultimately occur. Efficient repair or apoptosis represents extremes of control mechanisms. Misrepair can lead to fixation of damage. The changes in oncoprotein expression of three genes invo...

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Veröffentlicht in:Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 1995-09, Vol.4 (6), p.617
Hauptverfasser: Harney, J V, Seymour, C B, Murphy, D M, Mothersill, C
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Sprache:eng
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