Enhanced Expression of the Inhibitory Protein Gi2α and Decreased Activity of Adenylyl Cyclase in Lymphocytes of Abstinent Alcoholics

Ethanol exposure alters signal transduction through the adenylyl cyclase (AC) system. To elucidate the basis for this effect, we investigated the AC system in peripheral lymphocytes from abstinent alcoholic men (n= 22), actively drinking alcoholic men (n= 41), and nonalcoholic control men (n= 16). I...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Alcoholism, clinical and experimental research clinical and experimental research, 1993-04, Vol.17 (2), p.315-320
Hauptverfasser:	Waltman, Claire, Levine, Michael A., McCaul, M. E., Svikis, D. S., Wand, Gary S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclase Adenylyl Cyclases - blood Adult Alcoholism Alcoholism - genetics Alcoholism - rehabilitation Alcoholism and acute alcohol poisoning Biological and medical sciences Blotting, Northern Female Gene Expression Regulation - physiology GTP-Binding Proteins - antagonists & inhibitors GTP-Binding Proteins - genetics Guanine Nucleotide Binding Protein Humans Lymphocytes - enzymology Male Medical sciences Middle Aged Signal Transduction Signal Transduction - genetics Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!