The paradoxical effect of tumor necrosis factor alpha (TNF-alpha) in endotoxin-induced uveitis

To investigate the role of TNF-alpha in endotoxin-induced uveitis (EIU) in mice. To neutralize TNF-alpha activity, mice were pretreated with either repeated injections of this cytokine or a single injection of antibody against it. The mice were then injected intraperitoneally with 500 micrograms end...

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Veröffentlicht in:	Investigative ophthalmology & visual science 1993-09, Vol.34 (10), p.2911-2917
Hauptverfasser:	Kasner, L, Chan, CC, Whitcup, SM, Gery, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Bacterial Toxins Biological and medical sciences Disease Models, Animal Endotoxins Female Medical sciences Mice Mice, Inbred C3H Ophthalmology Recombinant Proteins - immunology Salmonella typhimurium Tumor Necrosis Factor-alpha - immunology Uvea diseases Uveitis, Anterior - immunology Uveitis, Anterior - pathology Uveitis, Anterior - prevention & control
Online-Zugang:	Volltext
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