Fate of early carcinogen-induced lesions in tracheal epithelium

Hyperplastic-metaplastic lesions were produced in transplanted rat tracheas by exposure to 310 or 75 mug 7,12-dimethylbenz(a)anthracene or to 650 mug benzo(a)pyrene delivered over a 2-week exposure period. Tissue recovery was studied for up to 16 weeks. After cessation of carcinogen exposure, most o...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1976-07, Vol.36 (7 PT 2), p.2659
Hauptverfasser:	Griesemer, R A, Nettesheim, P, Marchok, A C
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene Animals Benzopyrenes Carcinogens - administration & dosage Cell Transformation, Neoplastic Epithelium - pathology Hyperplasia - chemically induced Neoplasms, Experimental Precancerous Conditions - pathology Rats Time Factors Tracheal Neoplasms - chemically induced Tracheal Neoplasms - pathology
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