Epidermal Growth Factor is a Positive in Vivo Regulator of CTP: Cholinephosphate Cytidylyltransferase

CTP: cholinephosphate cytidylyltransferase (CT) is a key enzyme required for surfactant phosphatidylcholine synthesis, and its activity is regulated by lung lipids. This study evaluated the effect of epidermal growth factor (EGF) on the phospholipid content and the expression of CT in the lung follo...

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Veröffentlicht in:	Experimental lung research 1994, Vol.20 (1), p.1-11
Hauptverfasser:	Mallampalli, Rama K., Salome, Ronald G., Hunninghake, Gary W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Choline-Phosphate Cytidylyltransferase Cytosol - enzymology Enzyme Activation - drug effects Epidermal Growth Factor - pharmacology Lung - drug effects Lung - enzymology Lung - metabolism Microsomes - enzymology Nucleotidyltransferases - metabolism Phosphatidylcholines - metabolism Phospholipids - metabolism Pulmonary Surfactants - metabolism Rats Rats, Sprague-Dawley
Online-Zugang:	Volltext
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