Cortical lenticular opacification: distribution and location in a longitudinal study
To examine the distribution of cortical opacification of the lens by lens quadrant in a longitudinal study. In 1990, a follow-up assessment of a cohort of Chesapeake Bay watermen, initially studied in 1985, was performed. Four hundred thirty-seven subjects (834 eyes) had gradable cortical photograph...
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| Veröffentlicht in: | Investigative ophthalmology & visual science 1994-02, Vol.35 (2), p.363-366 |
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| container_title | Investigative ophthalmology & visual science |
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| creator | Schein, OD West, S Munoz, B Vitale, S Maguire, M Taylor, HR Bressler, NM |
| description | To examine the distribution of cortical opacification of the lens by lens quadrant in a longitudinal study.
In 1990, a follow-up assessment of a cohort of Chesapeake Bay watermen, initially studied in 1985, was performed. Four hundred thirty-seven subjects (834 eyes) had gradable cortical photographs for at least one eye in both 1985 and 1990. Cortical photographs were graded by both estimating total area and determining the quadrant with the greatest degree of cortical opacification.
The prevalence and severity of cortical opacification increased with age with a high degree of concordance (84%) between eyes. For the 47 eyes with cortical opacification > or = 1/8 at baseline, the principal locations of opacification were: inferonasal 63.8%, inferotemporal 17.0%, superonasal 6.4%, and superotemporal 12.8% (P < 0.001, compared with equal distribution by quadrant). Five-year development of new cortical opacification and five-year progression of existing cortical opacification showed even greater preferential occurrence in the inferonasal quadrant of the lens.
In this population, the inferonasal quadrant of the lens is the principal site of cortical opacification in both cross-sectional and longitudinal assessment. This finding is consistent with the hypothesis that sunlight exposure is a significant risk factor for cortical opacification. |
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In 1990, a follow-up assessment of a cohort of Chesapeake Bay watermen, initially studied in 1985, was performed. Four hundred thirty-seven subjects (834 eyes) had gradable cortical photographs for at least one eye in both 1985 and 1990. Cortical photographs were graded by both estimating total area and determining the quadrant with the greatest degree of cortical opacification.
The prevalence and severity of cortical opacification increased with age with a high degree of concordance (84%) between eyes. For the 47 eyes with cortical opacification > or = 1/8 at baseline, the principal locations of opacification were: inferonasal 63.8%, inferotemporal 17.0%, superonasal 6.4%, and superotemporal 12.8% (P < 0.001, compared with equal distribution by quadrant). Five-year development of new cortical opacification and five-year progression of existing cortical opacification showed even greater preferential occurrence in the inferonasal quadrant of the lens.
In this population, the inferonasal quadrant of the lens is the principal site of cortical opacification in both cross-sectional and longitudinal assessment. This finding is consistent with the hypothesis that sunlight exposure is a significant risk factor for cortical opacification.</description><identifier>ISSN: 0146-0404</identifier><identifier>EISSN: 1552-5783</identifier><identifier>PMID: 8112982</identifier><identifier>CODEN: IOVSDA</identifier><language>eng</language><publisher>Rockville, MD: ARVO</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Cataract - epidemiology ; Cataract - etiology ; Cataract - pathology ; Cohort Studies ; Follow-Up Studies ; Humans ; Lens Cortex, Crystalline - pathology ; Lens Cortex, Crystalline - radiation effects ; Lens diseases ; Longitudinal Studies ; Male ; Maryland - epidemiology ; Medical sciences ; Middle Aged ; Ophthalmology ; Photography ; Prevalence ; Radiation Injuries - epidemiology ; Radiation Injuries - etiology ; Radiation Injuries - pathology ; Risk Factors ; Ultraviolet Rays - adverse effects</subject><ispartof>Investigative ophthalmology & visual science, 1994-02, Vol.35 (2), p.363-366</ispartof><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3938622$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8112982$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schein, OD</creatorcontrib><creatorcontrib>West, S</creatorcontrib><creatorcontrib>Munoz, B</creatorcontrib><creatorcontrib>Vitale, S</creatorcontrib><creatorcontrib>Maguire, M</creatorcontrib><creatorcontrib>Taylor, HR</creatorcontrib><creatorcontrib>Bressler, NM</creatorcontrib><title>Cortical lenticular opacification: distribution and location in a longitudinal study</title><title>Investigative ophthalmology & visual science</title><addtitle>Invest Ophthalmol Vis Sci</addtitle><description>To examine the distribution of cortical opacification of the lens by lens quadrant in a longitudinal study.
In 1990, a follow-up assessment of a cohort of Chesapeake Bay watermen, initially studied in 1985, was performed. Four hundred thirty-seven subjects (834 eyes) had gradable cortical photographs for at least one eye in both 1985 and 1990. Cortical photographs were graded by both estimating total area and determining the quadrant with the greatest degree of cortical opacification.
The prevalence and severity of cortical opacification increased with age with a high degree of concordance (84%) between eyes. For the 47 eyes with cortical opacification > or = 1/8 at baseline, the principal locations of opacification were: inferonasal 63.8%, inferotemporal 17.0%, superonasal 6.4%, and superotemporal 12.8% (P < 0.001, compared with equal distribution by quadrant). Five-year development of new cortical opacification and five-year progression of existing cortical opacification showed even greater preferential occurrence in the inferonasal quadrant of the lens.
In this population, the inferonasal quadrant of the lens is the principal site of cortical opacification in both cross-sectional and longitudinal assessment. This finding is consistent with the hypothesis that sunlight exposure is a significant risk factor for cortical opacification.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Cataract - epidemiology</subject><subject>Cataract - etiology</subject><subject>Cataract - pathology</subject><subject>Cohort Studies</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Lens Cortex, Crystalline - pathology</subject><subject>Lens Cortex, Crystalline - radiation effects</subject><subject>Lens diseases</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Maryland - epidemiology</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Ophthalmology</subject><subject>Photography</subject><subject>Prevalence</subject><subject>Radiation Injuries - epidemiology</subject><subject>Radiation Injuries - etiology</subject><subject>Radiation Injuries - pathology</subject><subject>Risk Factors</subject><subject>Ultraviolet Rays - adverse effects</subject><issn>0146-0404</issn><issn>1552-5783</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9T01LwzAYDqLMOf0JQg96LKR5kzb1JkWnMPDSe3nbJGska0fSUvbvzdjw9HzywHND1pkQLBWFhFuyphnPU8opvycPIfxSyrKM0RVZyYilZGtSV6OfbIcucXqIZHbok_GInTXRnew4vCXKhsnbdj6rBAeVuPESJTbqqIa9nWZlh7gSIjk9kjuDLuinK25I_flRV1_p7mf7Xb3v0p7lYkqLnAshdY4GtWRKQoFGgyk7kLxtQWhW8EIwYajRLQLjXcYNLxQTbamVhg15vswe5_agVXP09oD-1FzPxfzlmmOID43HobPhvwYlyJyda6-XWm_3_WK9bsIBnYujWbMsC4iGNZAD_AHTTGeP</recordid><startdate>19940201</startdate><enddate>19940201</enddate><creator>Schein, OD</creator><creator>West, S</creator><creator>Munoz, B</creator><creator>Vitale, S</creator><creator>Maguire, M</creator><creator>Taylor, HR</creator><creator>Bressler, NM</creator><general>ARVO</general><general>Association for Research in Vision and Ophtalmology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>19940201</creationdate><title>Cortical lenticular opacification: distribution and location in a longitudinal study</title><author>Schein, OD ; West, S ; Munoz, B ; Vitale, S ; Maguire, M ; Taylor, HR ; Bressler, NM</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h265t-764558e6afae82d837afe3f9c384bb35e2747525f0feba324c14f47d25b9ede3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Cataract - epidemiology</topic><topic>Cataract - etiology</topic><topic>Cataract - pathology</topic><topic>Cohort Studies</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Lens Cortex, Crystalline - pathology</topic><topic>Lens Cortex, Crystalline - radiation effects</topic><topic>Lens diseases</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Maryland - epidemiology</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Ophthalmology</topic><topic>Photography</topic><topic>Prevalence</topic><topic>Radiation Injuries - epidemiology</topic><topic>Radiation Injuries - etiology</topic><topic>Radiation Injuries - pathology</topic><topic>Risk Factors</topic><topic>Ultraviolet Rays - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schein, OD</creatorcontrib><creatorcontrib>West, S</creatorcontrib><creatorcontrib>Munoz, B</creatorcontrib><creatorcontrib>Vitale, S</creatorcontrib><creatorcontrib>Maguire, M</creatorcontrib><creatorcontrib>Taylor, HR</creatorcontrib><creatorcontrib>Bressler, NM</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Investigative ophthalmology & visual science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schein, OD</au><au>West, S</au><au>Munoz, B</au><au>Vitale, S</au><au>Maguire, M</au><au>Taylor, HR</au><au>Bressler, NM</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cortical lenticular opacification: distribution and location in a longitudinal study</atitle><jtitle>Investigative ophthalmology & visual science</jtitle><addtitle>Invest Ophthalmol Vis Sci</addtitle><date>1994-02-01</date><risdate>1994</risdate><volume>35</volume><issue>2</issue><spage>363</spage><epage>366</epage><pages>363-366</pages><issn>0146-0404</issn><eissn>1552-5783</eissn><coden>IOVSDA</coden><abstract>To examine the distribution of cortical opacification of the lens by lens quadrant in a longitudinal study.
In 1990, a follow-up assessment of a cohort of Chesapeake Bay watermen, initially studied in 1985, was performed. Four hundred thirty-seven subjects (834 eyes) had gradable cortical photographs for at least one eye in both 1985 and 1990. Cortical photographs were graded by both estimating total area and determining the quadrant with the greatest degree of cortical opacification.
The prevalence and severity of cortical opacification increased with age with a high degree of concordance (84%) between eyes. For the 47 eyes with cortical opacification > or = 1/8 at baseline, the principal locations of opacification were: inferonasal 63.8%, inferotemporal 17.0%, superonasal 6.4%, and superotemporal 12.8% (P < 0.001, compared with equal distribution by quadrant). Five-year development of new cortical opacification and five-year progression of existing cortical opacification showed even greater preferential occurrence in the inferonasal quadrant of the lens.
In this population, the inferonasal quadrant of the lens is the principal site of cortical opacification in both cross-sectional and longitudinal assessment. This finding is consistent with the hypothesis that sunlight exposure is a significant risk factor for cortical opacification.</abstract><cop>Rockville, MD</cop><pub>ARVO</pub><pmid>8112982</pmid><tpages>4</tpages></addata></record> |
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| ispartof | Investigative ophthalmology & visual science, 1994-02, Vol.35 (2), p.363-366 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Aged Aged, 80 and over Biological and medical sciences Cataract - epidemiology Cataract - etiology Cataract - pathology Cohort Studies Follow-Up Studies Humans Lens Cortex, Crystalline - pathology Lens Cortex, Crystalline - radiation effects Lens diseases Longitudinal Studies Male Maryland - epidemiology Medical sciences Middle Aged Ophthalmology Photography Prevalence Radiation Injuries - epidemiology Radiation Injuries - etiology Radiation Injuries - pathology Risk Factors Ultraviolet Rays - adverse effects |
| title | Cortical lenticular opacification: distribution and location in a longitudinal study |
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