Serum levels of soluble CD8, neopterin, beta 2-microglobulin and p24 antigen as indicators of disease progression in children with AIDS on zidovudine therapy

To test the hypothesis that serum levels of soluble markers in children change after initiation of zidovudine therapy and that the extent and pattern of these longitudinal changes correlates with clinical outcome. We measured serum levels of soluble CD8, neopterin, beta 2-microglobulin (beta 2M), an...

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Veröffentlicht in:	AIDS (London) 1993-03, Vol.7 (3), p.369
Hauptverfasser:	Siller, L, Martin, N L, Kostuchenko, P, Beckett, L, Rautonen, J, Cheng, S C, Wara, D W
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - blood Acquired Immunodeficiency Syndrome - drug therapy beta 2-Microglobulin - analysis Biomarkers - blood Biopterins - analogs & derivatives Biopterins - analysis CD4-Positive T-Lymphocytes CD8 Antigens - blood Child Child, Preschool Female HIV Core Protein p24 - blood Humans Infant Leukocyte Count Male Neopterin Predictive Value of Tests Prospective Studies Zidovudine - therapeutic use
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