Silver nitrate ophthalmic solution and chemical conjunctivities

The current status of nursery routines of prophylaxis against ophthalmia neonatorum were surveyed by mail questionnaire to 100 leading maternity hospitals. More than 20% of the respondents were not using silver nitrate, mainly because of chemical conjunctivitis. The clinical significance and inciden...

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Veröffentlicht in:Pediatrics (Evanston) 1975-09, Vol.56 (3), p.368
Hauptverfasser: Nishida, H, Risemberg, H M
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description The current status of nursery routines of prophylaxis against ophthalmia neonatorum were surveyed by mail questionnaire to 100 leading maternity hospitals. More than 20% of the respondents were not using silver nitrate, mainly because of chemical conjunctivitis. The clinical significance and incidence of chemical conjunctivitis were studied in 1,000 newborns whose eyes were handled differently. Rinsing after instillation of silver nitrate does not reduce the conjunctival irritation. Although 90% of the infants had conjunctivitis in the first hours of life, the majority cleared within 24 hours. Chemical conjunctivitis did not increase secondary infection, neither did it mask bacterial infection. Silver nitrate is effective in vitro against Neisseria gonorrhoeae and Staphylococcus aureus in a concentration of 0.1% and against Escherichia coli in a concentration of 0.01%.
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More than 20% of the respondents were not using silver nitrate, mainly because of chemical conjunctivitis. The clinical significance and incidence of chemical conjunctivitis were studied in 1,000 newborns whose eyes were handled differently. Rinsing after instillation of silver nitrate does not reduce the conjunctival irritation. Although 90% of the infants had conjunctivitis in the first hours of life, the majority cleared within 24 hours. Chemical conjunctivitis did not increase secondary infection, neither did it mask bacterial infection. Silver nitrate is effective in vitro against Neisseria gonorrhoeae and Staphylococcus aureus in a concentration of 0.1% and against Escherichia coli in a concentration of 0.01%.</description><identifier>ISSN: 0031-4005</identifier><identifier>PMID: 808790</identifier><language>eng</language><publisher>United States</publisher><subject>Conjunctivitis - chemically induced ; Dose-Response Relationship, Drug ; Escherichia coli - drug effects ; Humans ; Infant, Newborn ; Neisseria gonorrhoeae - drug effects ; Nurseries, Hospital ; Ophthalmia Neonatorum - prevention &amp; control ; Ophthalmic Solutions ; Silver Nitrate - administration &amp; dosage ; Silver Nitrate - adverse effects ; Silver Nitrate - therapeutic use ; Staphylococcus aureus - drug effects</subject><ispartof>Pediatrics (Evanston), 1975-09, Vol.56 (3), p.368</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/808790$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nishida, H</creatorcontrib><creatorcontrib>Risemberg, H M</creatorcontrib><title>Silver nitrate ophthalmic solution and chemical conjunctivities</title><title>Pediatrics (Evanston)</title><addtitle>Pediatrics</addtitle><description>The current status of nursery routines of prophylaxis against ophthalmia neonatorum were surveyed by mail questionnaire to 100 leading maternity hospitals. More than 20% of the respondents were not using silver nitrate, mainly because of chemical conjunctivitis. The clinical significance and incidence of chemical conjunctivitis were studied in 1,000 newborns whose eyes were handled differently. Rinsing after instillation of silver nitrate does not reduce the conjunctival irritation. Although 90% of the infants had conjunctivitis in the first hours of life, the majority cleared within 24 hours. Chemical conjunctivitis did not increase secondary infection, neither did it mask bacterial infection. 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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Conjunctivitis - chemically induced
Dose-Response Relationship, Drug
Escherichia coli - drug effects
Humans
Infant, Newborn
Neisseria gonorrhoeae - drug effects
Nurseries, Hospital
Ophthalmia Neonatorum - prevention & control
Ophthalmic Solutions
Silver Nitrate - administration & dosage
Silver Nitrate - adverse effects
Silver Nitrate - therapeutic use
Staphylococcus aureus - drug effects
title Silver nitrate ophthalmic solution and chemical conjunctivities
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