Hemorrhagic cystitis in bone marrow transplantation

Patients undergoing bone marrow transplantation are at risk for hemorrhagic cystitis despite appropriate preventive measures. This complication could have an impact on patient survival and other outcome variables. A retrospective study of patients subjected to bone marrow transplantation was conduct...

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Veröffentlicht in:Urology (Ridgewood, N.J.) N.J.), 1994-09, Vol.44 (3), p.322-328
Hauptverfasser: YANG, C. C, HURD, D. D, CASE, L. D, ASSIMOS, D. G
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container_title Urology (Ridgewood, N.J.)
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creator YANG, C. C
HURD, D. D
CASE, L. D
ASSIMOS, D. G
description Patients undergoing bone marrow transplantation are at risk for hemorrhagic cystitis despite appropriate preventive measures. This complication could have an impact on patient survival and other outcome variables. A retrospective study of patients subjected to bone marrow transplantation was conducted to determine risk factors for hemorrhagic cystitis and evaluate the impact of hemorrhagic cystitis on certain outcome variables. Patients who experienced hemorrhagic cystitis received various forms of therapy, at the discretion of the treating physician. Hemorrhagic cystitis occurred more frequently in younger patients and those undergoing allogeneic transplantation. The occurrence of hemorrhagic cystitis was associated with increased hospital costs, length of hospitalization, and mortality. Gender, race, type of malignancy, other pretransplantation comorbidity, and the occurrence of other peritransplantation complications were not associated with occurrence of hemorrhagic cystitis. Hemorrhagic cystitis is a significant complication of bone marrow transplantation, which influences economic and survival outcome. Since the number of bone marrow transplants being performed is increasing, urologists should be prepared to play an active role in treating patients who experience this complication.
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Gender, race, type of malignancy, other pretransplantation comorbidity, and the occurrence of other peritransplantation complications were not associated with occurrence of hemorrhagic cystitis. Hemorrhagic cystitis is a significant complication of bone marrow transplantation, which influences economic and survival outcome. 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The occurrence of hemorrhagic cystitis was associated with increased hospital costs, length of hospitalization, and mortality. Gender, race, type of malignancy, other pretransplantation comorbidity, and the occurrence of other peritransplantation complications were not associated with occurrence of hemorrhagic cystitis. Hemorrhagic cystitis is a significant complication of bone marrow transplantation, which influences economic and survival outcome. 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Urinary tract diseases</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Survival Analysis</topic><topic>Transplantation, Homologous - adverse effects</topic><topic>Urinary system involvement in other diseases. Miscellaneous</topic><topic>Urinary tract. Prostate gland</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>YANG, C. C</creatorcontrib><creatorcontrib>HURD, D. D</creatorcontrib><creatorcontrib>CASE, L. D</creatorcontrib><creatorcontrib>ASSIMOS, D. G</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>YANG, C. C</au><au>HURD, D. D</au><au>CASE, L. D</au><au>ASSIMOS, D. G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hemorrhagic cystitis in bone marrow transplantation</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>1994-09-01</date><risdate>1994</risdate><volume>44</volume><issue>3</issue><spage>322</spage><epage>328</epage><pages>322-328</pages><issn>0090-4295</issn><eissn>1527-9995</eissn><coden>URGYAZ</coden><abstract>Patients undergoing bone marrow transplantation are at risk for hemorrhagic cystitis despite appropriate preventive measures. This complication could have an impact on patient survival and other outcome variables. A retrospective study of patients subjected to bone marrow transplantation was conducted to determine risk factors for hemorrhagic cystitis and evaluate the impact of hemorrhagic cystitis on certain outcome variables. Patients who experienced hemorrhagic cystitis received various forms of therapy, at the discretion of the treating physician. Hemorrhagic cystitis occurred more frequently in younger patients and those undergoing allogeneic transplantation. The occurrence of hemorrhagic cystitis was associated with increased hospital costs, length of hospitalization, and mortality. Gender, race, type of malignancy, other pretransplantation comorbidity, and the occurrence of other peritransplantation complications were not associated with occurrence of hemorrhagic cystitis. Hemorrhagic cystitis is a significant complication of bone marrow transplantation, which influences economic and survival outcome. Since the number of bone marrow transplants being performed is increasing, urologists should be prepared to play an active role in treating patients who experience this complication.</abstract><cop>New York, NY</cop><pub>Elsevier Science</pub><pmid>8073547</pmid><doi>10.1016/S0090-4295(94)80085-5</doi><tpages>7</tpages></addata></record>
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Adolescent
Adult
Algorithms
Biological and medical sciences
Bone Marrow Transplantation - adverse effects
Bone Marrow Transplantation - mortality
Cystitis - etiology
Cystitis - mortality
Cystitis - therapy
Female
Hematuria - economics
Hematuria - etiology
Hematuria - mortality
Hemorrhage - etiology
Hemorrhage - mortality
Hemorrhage - therapy
Humans
Length of Stay - economics
Male
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Retrospective Studies
Risk Factors
Survival Analysis
Transplantation, Homologous - adverse effects
Urinary system involvement in other diseases. Miscellaneous
Urinary tract. Prostate gland
title Hemorrhagic cystitis in bone marrow transplantation
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