Extraretinal neovascularization induced by hypoxic episodes in the neonatal rat

To test the hypothesis that hypoxia induces retinal neovascularization. To produce relative hypoxia in the avascular retina, newborn rats were exposed for 11 days to 80% oxygen interrupted daily by short episodes in room air. Episodes in room air lasted 1/2 hour or 1 hour followed by abrupt reintrod...

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Veröffentlicht in:	Investigative ophthalmology & visual science 1994-07, Vol.35 (8), p.3169-3177
Hauptverfasser:	Reynaud, X, Dorey, CK
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Biological and medical sciences Disease Models, Animal Dose-Response Relationship, Drug Female Humans Hypoxia - complications Image Processing, Computer-Assisted Infant, Newborn Medical sciences Ophthalmology Oxygen - adverse effects Oxygen Consumption Pregnancy Rats Rats, Sprague-Dawley Retinal Neovascularization - etiology Retinal Neovascularization - pathology Retinal Vessels - drug effects Retinal Vessels - pathology Retinopathies Retinopathy of Prematurity - etiology
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