In vitro mutational spectrum of aflatoxin B1 in the human hypoxanthine guanine phosphoribosyltransferase gene

The in vitro mutational spectrum of aflatoxin B1 (AFB1) in exon 3 of the human hypoxanthine guanine phosphoribosyltransferase gene in B-lymphoblasts was examined by a combination of polymerase chain reaction and denaturing gradient gel electrophoresis. The cell line used in this study contained an e...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1994-08, Vol.54 (16), p.4436-4441
Hauptverfasser:	CARIELLO, N. F, CUI, L, SKOPEK, T. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Aflatoxin B1 - toxicity Base Sequence Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Cell Line Chemical agents Exons - genetics Humans Hypoxanthine Phosphoribosyltransferase - genetics Medical sciences Molecular Sequence Data Point Mutation - genetics Tumors
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