Clinical pharmacokinetics of cyclophosphamide and metabolites with and without SR-2508

The pharmacokinetics of cyclophosphamide (CP) and several important metabolites was studied in detail in six patients receiving CP alone and with a radio- and chemosensitizing agent, SR-2508. CP at 1000 mg/m2 was either infused in 20 min alone or given 2 h before an infusion of SR-2508 at 5 g/m2 ove...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1994-12, Vol.54 (24), p.6421-6429
Hauptverfasser:	CHAN, K. K, HONG, P. S, TUTSCH, K, TRUMP, D. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Chemotherapy Cyclophosphamide - analogs & derivatives Cyclophosphamide - blood Cyclophosphamide - pharmacokinetics Cyclophosphamide - urine Etanidazole - pharmacokinetics Etanidazole - pharmacology Humans Medical sciences Pharmacology. Drug treatments Phosphoramide Mustards - blood Pyridines - blood Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!