α-particle-induced p53 protein expression in a rat lung epithelial cell strain

Other investigators have shown that both sparsely ionizing and UV radiation cause cell cycle arrest that is associated with increased expression of wild-type p53 protein. The effect of exposure to alpha-particles from 238Pu on the induction of the p53 protein has now been examined in cultured lung e...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1994-11, Vol.54 (22), p.5797-5800
Hauptverfasser:	HICKMAN, A. W, JARAMILLO, R. J, LECHNER, J. F, JOHNSON, N. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha Particles Animals Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Cells, Cultured DNA Damage Dose-Response Relationship, Radiation Epithelium - metabolism Epithelium - radiation effects Lung - metabolism Lung - radiation effects Male Medical sciences Physical agents Plutonium Rats Rats, Inbred F344 Time Factors Tumor Suppressor Protein p53 - biosynthesis Tumor Suppressor Protein p53 - radiation effects Tumors
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