Arimidex: a potent and selective fourth-generation aromatase inhibitor

Arimidex is a potent and selective aromatase inhibitor undergoing evaluation as a treatment for postmenopausal women with advanced breast cancer. Studies to determine the pharmacology of Arimidex were conducted in both animals and humans. In animals, Arimidex was selective for the aromatase enzyme,...

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Veröffentlicht in:	Breast cancer research and treatment 1994, Vol.30 (1), p.103
Hauptverfasser:	Plourde, P V, Dyroff, M, Dukes, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Anastrozole Animals Aromatase Inhibitors Breast Neoplasms - drug therapy Clinical Trials as Topic Dogs Estrogens - blood Female Hormones - blood In Vitro Techniques Macaca nemestrina Male Nitriles - adverse effects Nitriles - pharmacokinetics Nitriles - pharmacology Nitriles - therapeutic use Postmenopause Rats Triazoles - adverse effects Triazoles - pharmacokinetics Triazoles - pharmacology Triazoles - therapeutic use
Online-Zugang:	Volltext
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