The enterotoxin of Bacteroides fragilis is a metalloprotease

During the past decade, strains of Bacteroides fragilis that produce an enterotoxin have been implicated in diarrheal disease in animals and humans. The extracellular enterotoxin has been purified and characterized as a single polypeptide (Mr, approximately 20,000). Single specific primer-PCR was us...

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Veröffentlicht in:	Infection and Immunity 1995-01, Vol.63 (1), p.175-181
Hauptverfasser:	Moncrief, J.S. (Virginia Polytechnic Institute and State University, Blacksburg, VA.), Obiso, R. Jr, Barroso, L.A, Kling, J.J, Wright, R.L, Van Tassell, R.L, Lyerly, D.M, Wilkins, T.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism ACTIVIDAD ENZIMATICA ACTIVITE ENZYMATIQUE Amino Acid Sequence Azo Compounds - metabolism Bacterial Toxins - genetics Bacterial Toxins - immunology Bacterial Toxins - metabolism Bacteriology BACTEROIDES Bacteroides fragilis Bacteroides fragilis - enzymology Bacteroides fragilis - genetics Base Sequence Biological and medical sciences CINC Cloning, Molecular Collagen - metabolism Collagenases - metabolism COMPOSICION QUIMICA COMPOSITION CHIMIQUE Consensus Sequence ENTEROTOXINAS ENTEROTOXINE Escherichia coli - genetics EXPRESION GENICA EXPRESSION DES GENES Fundamental and applied biological sciences. Psychology GENE GENES Genes, Bacterial - genetics Metalloendopeptidases - antagonists & inhibitors Metalloendopeptidases - genetics Metalloendopeptidases - immunology Metalloendopeptidases - metabolism Microbiology Molecular Sequence Data Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Polymerase Chain Reaction - methods PROTEASAS PROTEASE PROTEOLISIS PROTEOLYSE RECOMBINACION RECOMBINAISON Recombinant Proteins - immunology SECUENCIA NUCLEICA Sequence Analysis, DNA Sequence Homology, Amino Acid SEQUENCE NUCLEIQUE Substrate Specificity TOXICIDAD TOXICITE TOXINAS TOXINE ZINC Zinc - analysis
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