Receptor‐Mediated Desensitisation of Histamine H1 Receptor‐Stimulated Inositol Phosphate Production and Calcium Mobilisation in GT1‐7 Neuronal Cells Is Independent of Protein Kinase C

: GT1‐7 cells, a clonal line derived from specific tumours of gonadotropin‐releasing hormone‐secreting neurons from mouse hypothalamus, were used as a model system to investigate the cellular mechanisms underlying the histamine H1 receptor‐mediated desensitisation. GT1‐7 cells contain H1 receptors,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurochemistry 1995-07, Vol.65 (1), p.160-169
Hauptverfasser:	Zamani, M. Reza, Dupere, Jonathan R. B., Bristow, David R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport Calcium - agonists Calcium - metabolism Desensitisation Histamine - physiology Histamine H1 receptor Inositol phosphates Inositol Phosphates - biosynthesis Intracellular calcium Intracellular Membranes - metabolism Mice Neurons - metabolism Osmolar Concentration Protein kinase C Protein Kinase C - antagonists & inhibitors Protein Kinase C - physiology Receptors, Histamine H1 - physiology Tetradecanoylphorbol Acetate - pharmacology Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!