The spatial accuracy of cellular dose estimates obtained from 3D reconstructed serial tissue autoradiographs

In order to better predict and understand the effects of radiopharmaceuticals used for therapy, it is necessary to determine more accurately the radiation absorbed dose to cells in tissue. Using thin-section autoradiography, the spatial distribution of sources relative to the cells can be obtained f...

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Veröffentlicht in:	Physics in medicine & biology 1995-01, Vol.40 (1), p.163-180
Hauptverfasser:	Humm, J L, Macklis, R M, Lu, X Q, Yang, Y, Bump, K, Beresford, B, Chin, L M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Applied radiobiology (equipment, dosimetry...) Autoradiography - instrumentation Autoradiography - methods Biological and medical sciences Biological effects of radiation Fundamental and applied biological sciences. Psychology Indium Radioisotopes - pharmacokinetics Indium Radioisotopes - therapeutic use Isoantibodies Kidney - diagnostic imaging Liver - diagnostic imaging Lymphoma, T-Cell - radiotherapy Mice Mice, Inbred C57BL Pentetic Acid Radioimmunotherapy - methods Radionuclide Imaging Radiotherapy Dosage Reproducibility of Results Spleen - diagnostic imaging Tissue Distribution Tissues, organs and organisms biophysics
Online-Zugang:	Volltext
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