Mutagen sensitivity in upper aerodigestive tract cancer: a case-control analysis

Variability in DNA repair capability may be a determinant of interindividual difference in susceptibility to carcinogenic exposures. A cytogenetic assay which quantifies chromosomal breakage induced by in vitro exposure to a clastogen provides an indirect measure of repair. We report the results of...

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Veröffentlicht in:	Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 1993-07, Vol.2 (4), p.329
Hauptverfasser:	Spitz, M R, Fueger, J J, Halabi, S, Schantz, S P, Sample, D, Hsu, T C
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Drinking - adverse effects Bleomycin - adverse effects Carcinoma, Squamous Cell - etiology Carcinoma, Squamous Cell - genetics Case-Control Studies Chromosome Aberrations - genetics Chromosomes - drug effects Disease Susceptibility DNA Damage Female Humans Laryngeal Neoplasms - etiology Laryngeal Neoplasms - genetics Male Middle Aged Mouth Neoplasms - etiology Mouth Neoplasms - genetics Mutagens - adverse effects Odds Ratio Pharyngeal Neoplasms - etiology Pharyngeal Neoplasms - genetics Plants, Toxic Risk Factors Smoking - adverse effects Tobacco, Smokeless - adverse effects
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