A case of acute renal failure due to ethylene glycol intoxication
We describe an 18-year-old man with acute renal failure due to inadvertent ingestion of antifreeze that contained ethylene glycol (EG). A relatively small amount of EG was ingested, but nausea and vomiting were observed soon after ingestion. During admission to a local hospital, consciousness became...
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Veröffentlicht in: | Nihon Jinzo Gakkai shi 1995, Vol.37(6), pp.353-356 |
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container_title | Nihon Jinzo Gakkai shi |
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creator | TADOKORO, Masato OZONO, Yoshiyuki HARA, Kohei TAGUCHI, Takashi HARADA, Takashi IDEGUCHI, Michiko SENJU, Masahiro |
description | We describe an 18-year-old man with acute renal failure due to inadvertent ingestion of antifreeze that contained ethylene glycol (EG). A relatively small amount of EG was ingested, but nausea and vomiting were observed soon after ingestion. During admission to a local hospital, consciousness became impaired and generalized convulsion was noted. He was transferred to our hospital because of rapid deterioration of renal function. Emergency hemodialysis was begun. The patient underwent one treatment session of hemodialysis each day, for a total of 8 hemodialytic sessions before his renal function recovered. Examination of the renal biopsy specimen revealed degeneration of the renal tubular epithelium and presence of intratubular calcium oxalate crystals. The clinical features of the patient were mild except for acute renal failure. These findings suggest that even a small amount of EG will have toxic effects on the kidney. |
doi_str_mv | 10.14842/jpnjnephrol1959.37.353 |
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A relatively small amount of EG was ingested, but nausea and vomiting were observed soon after ingestion. During admission to a local hospital, consciousness became impaired and generalized convulsion was noted. He was transferred to our hospital because of rapid deterioration of renal function. Emergency hemodialysis was begun. The patient underwent one treatment session of hemodialysis each day, for a total of 8 hemodialytic sessions before his renal function recovered. Examination of the renal biopsy specimen revealed degeneration of the renal tubular epithelium and presence of intratubular calcium oxalate crystals. The clinical features of the patient were mild except for acute renal failure. 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A relatively small amount of EG was ingested, but nausea and vomiting were observed soon after ingestion. During admission to a local hospital, consciousness became impaired and generalized convulsion was noted. He was transferred to our hospital because of rapid deterioration of renal function. Emergency hemodialysis was begun. The patient underwent one treatment session of hemodialysis each day, for a total of 8 hemodialytic sessions before his renal function recovered. Examination of the renal biopsy specimen revealed degeneration of the renal tubular epithelium and presence of intratubular calcium oxalate crystals. The clinical features of the patient were mild except for acute renal failure. These findings suggest that even a small amount of EG will have toxic effects on the kidney.</description><subject>Acute Kidney Injury - chemically induced</subject><subject>Acute Kidney Injury - pathology</subject><subject>Acute Kidney Injury - therapy</subject><subject>Adolescent</subject><subject>Calcium Oxalate - metabolism</subject><subject>Ethylene Glycol</subject><subject>ethylene glycol, acute renal failure, hemodialysis, calcium oxalate crystal</subject><subject>Ethylene Glycols - poisoning</subject><subject>Humans</subject><subject>Kidney - metabolism</subject><subject>Kidney - pathology</subject><subject>Male</subject><subject>Renal Dialysis</subject><issn>0385-2385</issn><issn>1884-0728</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkM1qwzAQhEVpSUOaRyjVCzi1tJIsHUPoHw300p6NLK8SG8U2tgz129eQkEPnMHv4lmFnCXli6YYJLfhz3TV1g92xbwMz0mwg24CEG7JkWoskzbi-JcsUtEz4bPdkPQx1OksZJYAtyCJTs1K-JNstdXZA2npq3RiR9tjYQL2twtgjLUeksaUYj1PABukhTK4NtGpi-1s5G6u2eSB33oYB15e5Ij-vL9-792T_9fax2-6TGhiPiRGqUMAKhYzx-ULvhXCl8miV0VwWWQbOKMtkUXKpS52a0hcCoDQgubcAK_J4zu3G4oRl3vXVyfZTfqky888zr4doD3jlto-VC5j_-1kOWa4uJuG65Y62z7GBP6rJahU</recordid><startdate>1995</startdate><enddate>1995</enddate><creator>TADOKORO, Masato</creator><creator>OZONO, Yoshiyuki</creator><creator>HARA, Kohei</creator><creator>TAGUCHI, Takashi</creator><creator>HARADA, Takashi</creator><creator>IDEGUCHI, Michiko</creator><creator>SENJU, Masahiro</creator><general>Japanese Society of Nephrology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>1995</creationdate><title>A case of acute renal failure due to ethylene glycol intoxication</title><author>TADOKORO, Masato ; OZONO, Yoshiyuki ; HARA, Kohei ; TAGUCHI, Takashi ; HARADA, Takashi ; IDEGUCHI, Michiko ; SENJU, Masahiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j312t-946b631b6e112072ff44cd6fea69825b773c96a15bd258d809dfb433d9352fa33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Acute Kidney Injury - chemically induced</topic><topic>Acute Kidney Injury - pathology</topic><topic>Acute Kidney Injury - therapy</topic><topic>Adolescent</topic><topic>Calcium Oxalate - metabolism</topic><topic>Ethylene Glycol</topic><topic>ethylene glycol, acute renal failure, hemodialysis, calcium oxalate crystal</topic><topic>Ethylene Glycols - poisoning</topic><topic>Humans</topic><topic>Kidney - metabolism</topic><topic>Kidney - pathology</topic><topic>Male</topic><topic>Renal Dialysis</topic><toplevel>online_resources</toplevel><creatorcontrib>TADOKORO, Masato</creatorcontrib><creatorcontrib>OZONO, Yoshiyuki</creatorcontrib><creatorcontrib>HARA, Kohei</creatorcontrib><creatorcontrib>TAGUCHI, Takashi</creatorcontrib><creatorcontrib>HARADA, Takashi</creatorcontrib><creatorcontrib>IDEGUCHI, Michiko</creatorcontrib><creatorcontrib>SENJU, Masahiro</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Nihon Jinzo Gakkai shi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>TADOKORO, Masato</au><au>OZONO, Yoshiyuki</au><au>HARA, Kohei</au><au>TAGUCHI, Takashi</au><au>HARADA, Takashi</au><au>IDEGUCHI, Michiko</au><au>SENJU, Masahiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A case of acute renal failure due to ethylene glycol intoxication</atitle><jtitle>Nihon Jinzo Gakkai shi</jtitle><addtitle>Jpn J Nephrol</addtitle><date>1995</date><risdate>1995</risdate><volume>37</volume><issue>6</issue><spage>353</spage><epage>356</epage><pages>353-356</pages><issn>0385-2385</issn><eissn>1884-0728</eissn><abstract>We describe an 18-year-old man with acute renal failure due to inadvertent ingestion of antifreeze that contained ethylene glycol (EG). 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subjects | Acute Kidney Injury - chemically induced Acute Kidney Injury - pathology Acute Kidney Injury - therapy Adolescent Calcium Oxalate - metabolism Ethylene Glycol ethylene glycol, acute renal failure, hemodialysis, calcium oxalate crystal Ethylene Glycols - poisoning Humans Kidney - metabolism Kidney - pathology Male Renal Dialysis |
title | A case of acute renal failure due to ethylene glycol intoxication |
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