A case of acute renal failure due to ethylene glycol intoxication

We describe an 18-year-old man with acute renal failure due to inadvertent ingestion of antifreeze that contained ethylene glycol (EG). A relatively small amount of EG was ingested, but nausea and vomiting were observed soon after ingestion. During admission to a local hospital, consciousness became...

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Veröffentlicht in:Nihon Jinzo Gakkai shi 1995, Vol.37(6), pp.353-356
Hauptverfasser: TADOKORO, Masato, OZONO, Yoshiyuki, HARA, Kohei, TAGUCHI, Takashi, HARADA, Takashi, IDEGUCHI, Michiko, SENJU, Masahiro
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container_end_page 356
container_issue 6
container_start_page 353
container_title Nihon Jinzo Gakkai shi
container_volume 37
creator TADOKORO, Masato
OZONO, Yoshiyuki
HARA, Kohei
TAGUCHI, Takashi
HARADA, Takashi
IDEGUCHI, Michiko
SENJU, Masahiro
description We describe an 18-year-old man with acute renal failure due to inadvertent ingestion of antifreeze that contained ethylene glycol (EG). A relatively small amount of EG was ingested, but nausea and vomiting were observed soon after ingestion. During admission to a local hospital, consciousness became impaired and generalized convulsion was noted. He was transferred to our hospital because of rapid deterioration of renal function. Emergency hemodialysis was begun. The patient underwent one treatment session of hemodialysis each day, for a total of 8 hemodialytic sessions before his renal function recovered. Examination of the renal biopsy specimen revealed degeneration of the renal tubular epithelium and presence of intratubular calcium oxalate crystals. The clinical features of the patient were mild except for acute renal failure. These findings suggest that even a small amount of EG will have toxic effects on the kidney.
doi_str_mv 10.14842/jpnjnephrol1959.37.353
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subjects Acute Kidney Injury - chemically induced
Acute Kidney Injury - pathology
Acute Kidney Injury - therapy
Adolescent
Calcium Oxalate - metabolism
Ethylene Glycol
ethylene glycol, acute renal failure, hemodialysis, calcium oxalate crystal
Ethylene Glycols - poisoning
Humans
Kidney - metabolism
Kidney - pathology
Male
Renal Dialysis
title A case of acute renal failure due to ethylene glycol intoxication
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