Effect of isopropyl-beta-D-thiogalactopyranosid induction of the lac operon on the specificity of spontaneous and doxorubicin-induced mutations in Escherichia coli

Previous studies of doxorubicin-induced mutations employing F' lacl/lacO as an endogenous gene target have focused on properties of large deletions with 3' endpoints residing in the lacO region of the target gene. This study considers the influence of Lac repressor binding on the distribut...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Environmental and molecular mutagenesis 1995, Vol.26 (1), p.16
Hauptverfasser:	Veigl, M L, Donover, S P, Anderson, R D, Akst, L, Sedwick, C E, Sedwick, W D
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - genetics Base Composition Base Sequence beta-Galactosidase - biosynthesis Doxorubicin - pharmacology Enzyme Induction - drug effects Escherichia coli - drug effects Escherichia coli - genetics Escherichia coli Proteins Genes, Bacterial Isopropyl Thiogalactoside - pharmacology Lac Operon - drug effects Lac Repressors Molecular Sequence Data Mutagens - pharmacology Point Mutation Repressor Proteins - genetics Sequence Deletion Species Specificity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!