Overexpression of cellular activity and protein level of protein kinase FA/GSK-3α correlates with human thyroid tumor cell dedifferentiation

Computer analysis of protein phosphorylation sites sequence revealed that transcriptional factors and viral oncoproteins are prime targets for regulation of proline‐directed protein phosphorylation, suggesting an association of the proline‐directed protein kinase (PDPK) family with neoplastic transf...

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Veröffentlicht in:	Journal of cellular biochemistry 1995-08, Vol.58 (4), p.474-480
Hauptverfasser:	Lee, Tsong-Tze, Ho, Yat-Sen, Yu, Jau-Song, Yang, Shiaw-Der
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - enzymology Adenoma - pathology Amino Acid Sequence Antibodies Calcium-Calmodulin-Dependent Protein Kinases - analysis Calcium-Calmodulin-Dependent Protein Kinases - biosynthesis carcinogenesis Carcinoma - enzymology Carcinoma - pathology Cell Differentiation Female Gene Expression Glycogen Synthase Kinase 3 Humans Hyperplasia kinase FA/GSK-3α Male Microtubule-Associated Proteins - metabolism Molecular Sequence Data overexpression Peptides - chemical synthesis Peptides - immunology Reference Values thyroid Thyroid Gland - cytology Thyroid Gland - enzymology Thyroid Gland - pathology Thyroid Neoplasms - enzymology Thyroid Neoplasms - pathology tumor cell dedifferentiation
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