Selective effects of a bacterial infection (Actinobacillus pleuropneumoniae) on the hepatic clearances of caffeine, antipyrine, paracetamol, and indocyanine green in the pig

1. In order to investigate the effect of a bacterial acute phase response model on drug disposition in vivo, plasma clearances of antipyrine, caffeine, paracetamol and indocyanine green were investigated in the healthy and Actinobacillus pleuropneumoniae-infected pig. 2. Indocyanine green plasma and...

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Veröffentlicht in:	Xenobiotica 1995, Vol.25 (5), p.491-499
Hauptverfasser:	Monshouwer, M., Witkamp, R. F., Nijmeijer, S. M., Pijpers, A., Verheijden, J. H. M., Van Miert, A. S. J. P. A. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - pharmacokinetics Actinobacillus Infections - metabolism Actinobacillus pleuropneumoniae Animals Antipyrine - analogs & derivatives Antipyrine - pharmacokinetics Biological and medical sciences Caffeine - pharmacokinetics Creatinine - blood Creatinine - urine General pharmacology Indocyanine Green - pharmacokinetics Liver - metabolism Male Medical sciences Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments Swine
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