A Fertility Study of Male Employees Engaged in the Manufacture of Glycerine
The fertility status of male employees engaged in the production of chlorinated three-carbon compounds at Dow Chemical Company's Texas Division was investigated. Males who had not worked in the production of industrial chemicals for at least five years prior to the study period served as contro...
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| Veröffentlicht in: | J. Occup. Med.; (United States) 1980-02, Vol.22 (2), p.87-91 |
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| creator | Venable, J. R. McClimans, C. D. Flake, R. E. Dimick, D. B. |
| description | The fertility status of male employees engaged in the production of chlorinated three-carbon compounds at Dow Chemical Company's Texas Division was investigated. Males who had not worked in the production of industrial chemicals for at least five years prior to the study period served as controls. Data were obtained from a reproductive medical history, from hormone determinations, from a physician's examination, and from a semen analysis. Sperm counts and percent normal sperm forms were major study variables. Comparisons were made between the control and the study groups and within the study group only for duration of exposure, strength of exposure and a combination of the two. Specific chemical exposure subgroups within the study group were also com pared. Although the participation rate for the exposed group was relatively low (64%), results indicated no detrimental effect on fertility from exposure to chlorinated three-carbon compounds at levels occurring in the specified work environment. |
| doi_str_mv | 10.1097/00043764-198002000-00005 |
| format | Article |
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R. ; McClimans, C. D. ; Flake, R. E. ; Dimick, D. B.</creator><creatorcontrib>Venable, J. R. ; McClimans, C. D. ; Flake, R. E. ; Dimick, D. B. ; Dow Chemical U.S.A., Freeport, TX</creatorcontrib><description>The fertility status of male employees engaged in the production of chlorinated three-carbon compounds at Dow Chemical Company's Texas Division was investigated. Males who had not worked in the production of industrial chemicals for at least five years prior to the study period served as controls. Data were obtained from a reproductive medical history, from hormone determinations, from a physician's examination, and from a semen analysis. Sperm counts and percent normal sperm forms were major study variables. Comparisons were made between the control and the study groups and within the study group only for duration of exposure, strength of exposure and a combination of the two. Specific chemical exposure subgroups within the study group were also com pared. Although the participation rate for the exposed group was relatively low (64%), results indicated no detrimental effect on fertility from exposure to chlorinated three-carbon compounds at levels occurring in the specified work environment.</description><identifier>ISSN: 0096-1736</identifier><identifier>ISSN: 1076-2752</identifier><identifier>EISSN: 2332-3795</identifier><identifier>DOI: 10.1097/00043764-198002000-00005</identifier><identifier>PMID: 7373447</identifier><language>eng</language><publisher>United States: American Occupational Medical Association</publisher><subject>560306 - Chemicals Metabolism & Toxicology- Man- (-1987) ; Adult ; ALCOHOLS ; Allyl Compounds - adverse effects ; ANIMALS ; BIOLOGICAL EFFECTS ; Chemical Industry ; Environmental Exposure ; Epichlorohydrin - adverse effects ; FERTILITY ; Fertility - drug effects ; GAMETES ; GERM CELLS ; GLYCEROL ; Glycerol - adverse effects ; HAZARDS ; HEALTH HAZARDS ; Humans ; Hydrocarbons, Chlorinated - adverse effects ; HYDROXY COMPOUNDS ; INDUSTRIAL PLANTS ; Male ; MALES ; MAMMALS ; MAN ; MANUFACTURING ; MEN ; MORPHOLOGY ; OCCUPATIONAL DISEASES ; Occupations ; ORGANIC CHLORINE COMPOUNDS ; ORGANIC COMPOUNDS ; ORGANIC HALOGEN COMPOUNDS ; Original Articles ; PERSONNEL ; PRIMATES ; RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT ; Sperm Count ; Sperm Motility - drug effects ; SPERMATOZOA ; VERTEBRATES ; WORKING CONDITIONS</subject><ispartof>J. Occup. Med.; (United States), 1980-02, Vol.22 (2), p.87-91</ispartof><rights>Copyrighted American Occupational Medical Association</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c243t-4baac705f7be6012cab64a8d59eea4ae415d9d7e2ae4cd7cf648ac097339b5f13</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7373447$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/5578284$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Venable, J. R.</creatorcontrib><creatorcontrib>McClimans, C. D.</creatorcontrib><creatorcontrib>Flake, R. E.</creatorcontrib><creatorcontrib>Dimick, D. B.</creatorcontrib><creatorcontrib>Dow Chemical U.S.A., Freeport, TX</creatorcontrib><title>A Fertility Study of Male Employees Engaged in the Manufacture of Glycerine</title><title>J. Occup. Med.; (United States)</title><addtitle>J Occup Med</addtitle><description>The fertility status of male employees engaged in the production of chlorinated three-carbon compounds at Dow Chemical Company's Texas Division was investigated. Males who had not worked in the production of industrial chemicals for at least five years prior to the study period served as controls. Data were obtained from a reproductive medical history, from hormone determinations, from a physician's examination, and from a semen analysis. Sperm counts and percent normal sperm forms were major study variables. Comparisons were made between the control and the study groups and within the study group only for duration of exposure, strength of exposure and a combination of the two. Specific chemical exposure subgroups within the study group were also com pared. Although the participation rate for the exposed group was relatively low (64%), results indicated no detrimental effect on fertility from exposure to chlorinated three-carbon compounds at levels occurring in the specified work environment.</description><subject>560306 - Chemicals Metabolism & Toxicology- Man- (-1987)</subject><subject>Adult</subject><subject>ALCOHOLS</subject><subject>Allyl Compounds - adverse effects</subject><subject>ANIMALS</subject><subject>BIOLOGICAL EFFECTS</subject><subject>Chemical Industry</subject><subject>Environmental Exposure</subject><subject>Epichlorohydrin - adverse effects</subject><subject>FERTILITY</subject><subject>Fertility - drug effects</subject><subject>GAMETES</subject><subject>GERM CELLS</subject><subject>GLYCEROL</subject><subject>Glycerol - adverse effects</subject><subject>HAZARDS</subject><subject>HEALTH HAZARDS</subject><subject>Humans</subject><subject>Hydrocarbons, Chlorinated - adverse effects</subject><subject>HYDROXY COMPOUNDS</subject><subject>INDUSTRIAL PLANTS</subject><subject>Male</subject><subject>MALES</subject><subject>MAMMALS</subject><subject>MAN</subject><subject>MANUFACTURING</subject><subject>MEN</subject><subject>MORPHOLOGY</subject><subject>OCCUPATIONAL DISEASES</subject><subject>Occupations</subject><subject>ORGANIC CHLORINE COMPOUNDS</subject><subject>ORGANIC COMPOUNDS</subject><subject>ORGANIC HALOGEN COMPOUNDS</subject><subject>Original Articles</subject><subject>PERSONNEL</subject><subject>PRIMATES</subject><subject>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</subject><subject>Sperm Count</subject><subject>Sperm Motility - drug effects</subject><subject>SPERMATOZOA</subject><subject>VERTEBRATES</subject><subject>WORKING CONDITIONS</subject><issn>0096-1736</issn><issn>1076-2752</issn><issn>2332-3795</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM1OwzAQhC0EKqXwCEgW94B_4_hYVaUgijgAZ8txNm2qNKls95C3x6WlHFa7q5lZaT-EMCWPlGj1RAgRXOUio7oghKU1S0XkBRozzlnGlZaXaEyIzjOqeH6NbkLYJANnQo_QSHHFhVBj9DbFz-Bj0zZxwJ9xXw24r_G7bQHPt7u2HwACnncru4IKNx2Oa0hqt6-ti3sPB_OiHRz4poNbdFXbNsDdqU_Q9_P8a_aSLT8Wr7PpMnNM8JiJ0lqniKxVCTmhzNkyF7aopAawwoKgstKVApZGVylX56KwLn3NuS5lTfkEPRzv9iE2Jrgmglu7vuvARSOlKlghkqk4mpzvQ_BQm51vttYPhhJzYGj-GJozQ_PLMEXvj9HdvtxCdQ6eoP3rmxB7f5aFJJQKTvgPrmN1sQ</recordid><startdate>198002</startdate><enddate>198002</enddate><creator>Venable, J. R.</creator><creator>McClimans, C. D.</creator><creator>Flake, R. E.</creator><creator>Dimick, D. B.</creator><general>American Occupational Medical Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>198002</creationdate><title>A Fertility Study of Male Employees Engaged in the Manufacture of Glycerine</title><author>Venable, J. R. ; McClimans, C. D. ; Flake, R. E. ; Dimick, D. B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c243t-4baac705f7be6012cab64a8d59eea4ae415d9d7e2ae4cd7cf648ac097339b5f13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>560306 - Chemicals Metabolism & Toxicology- Man- (-1987)</topic><topic>Adult</topic><topic>ALCOHOLS</topic><topic>Allyl Compounds - adverse effects</topic><topic>ANIMALS</topic><topic>BIOLOGICAL EFFECTS</topic><topic>Chemical Industry</topic><topic>Environmental Exposure</topic><topic>Epichlorohydrin - adverse effects</topic><topic>FERTILITY</topic><topic>Fertility - drug effects</topic><topic>GAMETES</topic><topic>GERM CELLS</topic><topic>GLYCEROL</topic><topic>Glycerol - adverse effects</topic><topic>HAZARDS</topic><topic>HEALTH HAZARDS</topic><topic>Humans</topic><topic>Hydrocarbons, Chlorinated - adverse effects</topic><topic>HYDROXY COMPOUNDS</topic><topic>INDUSTRIAL PLANTS</topic><topic>Male</topic><topic>MALES</topic><topic>MAMMALS</topic><topic>MAN</topic><topic>MANUFACTURING</topic><topic>MEN</topic><topic>MORPHOLOGY</topic><topic>OCCUPATIONAL DISEASES</topic><topic>Occupations</topic><topic>ORGANIC CHLORINE COMPOUNDS</topic><topic>ORGANIC COMPOUNDS</topic><topic>ORGANIC HALOGEN COMPOUNDS</topic><topic>Original Articles</topic><topic>PERSONNEL</topic><topic>PRIMATES</topic><topic>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</topic><topic>Sperm Count</topic><topic>Sperm Motility - drug effects</topic><topic>SPERMATOZOA</topic><topic>VERTEBRATES</topic><topic>WORKING CONDITIONS</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Venable, J. R.</creatorcontrib><creatorcontrib>McClimans, C. D.</creatorcontrib><creatorcontrib>Flake, R. E.</creatorcontrib><creatorcontrib>Dimick, D. B.</creatorcontrib><creatorcontrib>Dow Chemical U.S.A., Freeport, TX</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>J. Occup. Med.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Venable, J. R.</au><au>McClimans, C. D.</au><au>Flake, R. E.</au><au>Dimick, D. B.</au><aucorp>Dow Chemical U.S.A., Freeport, TX</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Fertility Study of Male Employees Engaged in the Manufacture of Glycerine</atitle><jtitle>J. Occup. Med.; (United States)</jtitle><addtitle>J Occup Med</addtitle><date>1980-02</date><risdate>1980</risdate><volume>22</volume><issue>2</issue><spage>87</spage><epage>91</epage><pages>87-91</pages><issn>0096-1736</issn><issn>1076-2752</issn><eissn>2332-3795</eissn><abstract>The fertility status of male employees engaged in the production of chlorinated three-carbon compounds at Dow Chemical Company's Texas Division was investigated. Males who had not worked in the production of industrial chemicals for at least five years prior to the study period served as controls. Data were obtained from a reproductive medical history, from hormone determinations, from a physician's examination, and from a semen analysis. Sperm counts and percent normal sperm forms were major study variables. Comparisons were made between the control and the study groups and within the study group only for duration of exposure, strength of exposure and a combination of the two. Specific chemical exposure subgroups within the study group were also com pared. Although the participation rate for the exposed group was relatively low (64%), results indicated no detrimental effect on fertility from exposure to chlorinated three-carbon compounds at levels occurring in the specified work environment.</abstract><cop>United States</cop><pub>American Occupational Medical Association</pub><pmid>7373447</pmid><doi>10.1097/00043764-198002000-00005</doi><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 0096-1736 |
| ispartof | J. Occup. Med.; (United States), 1980-02, Vol.22 (2), p.87-91 |
| issn | 0096-1736 1076-2752 2332-3795 |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | 560306 - Chemicals Metabolism & Toxicology- Man- (-1987) Adult ALCOHOLS Allyl Compounds - adverse effects ANIMALS BIOLOGICAL EFFECTS Chemical Industry Environmental Exposure Epichlorohydrin - adverse effects FERTILITY Fertility - drug effects GAMETES GERM CELLS GLYCEROL Glycerol - adverse effects HAZARDS HEALTH HAZARDS Humans Hydrocarbons, Chlorinated - adverse effects HYDROXY COMPOUNDS INDUSTRIAL PLANTS Male MALES MAMMALS MAN MANUFACTURING MEN MORPHOLOGY OCCUPATIONAL DISEASES Occupations ORGANIC CHLORINE COMPOUNDS ORGANIC COMPOUNDS ORGANIC HALOGEN COMPOUNDS Original Articles PERSONNEL PRIMATES RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT Sperm Count Sperm Motility - drug effects SPERMATOZOA VERTEBRATES WORKING CONDITIONS |
| title | A Fertility Study of Male Employees Engaged in the Manufacture of Glycerine |
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