Dietary aflatoxin and copper acetate effects on various blood parameters in rats

The effects of copper acetate (CuAc) and aflatoxin (AFT) dietary supplements on serum vitamins A and E, albumin, cholesterol, and the formed elements of blood in male rats were investigated. The CuAc and AFT dietary supplements were 0.5% and 7.8 ppm respectively. Vitamins A and E, red blood cell cou...

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Veröffentlicht in:	Drug and chemical toxicology (New York, N.Y. 1978) N.Y. 1978), 1981, Vol.4 (2), p.113
Hauptverfasser:	Weekley, L B, Kimbrough, T D, Llewellyn, G C
Format:	Artikel
Sprache:	eng
Schlagworte:	Aflatoxins - toxicity Animals Blood Proteins - analysis Cholesterol - blood Copper - pharmacology Male Rats Rats, Inbred Strains Serum Albumin - analysis
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Zusammenfassung:	The effects of copper acetate (CuAc) and aflatoxin (AFT) dietary supplements on serum vitamins A and E, albumin, cholesterol, and the formed elements of blood in male rats were investigated. The CuAc and AFT dietary supplements were 0.5% and 7.8 ppm respectively. Vitamins A and E, red blood cell count (RBC), mean cell volume (MCV), mean cell hemoglobin content (MCHC) and hematocrit (Hct) were not significantly altered by either supplement while albumin and cholesterol was significantly elevated in groups receiving either CuAc or AFT. Serum hemoglobin (HBG) was depressed in animals receiving the AFT + CuAc supplement while the WBC count was depressed in both groups receiving CuAc while AFT had no effect.
ISSN:	0148-0545
DOI:	10.3109/01480548108998254