Biological and biochemical properties of Nonidet P40-solubilized and partially purified tumor-specific antigens of the transplantation type from plasma membranes of a methylcholanthrene-induced sarcoma

Tumor-specific transplantation antigen (TSTA) was solubilized from cell membranes of sarcoma Meth-A with non-ionic detergent Nonidet P40. Soluble TSTA was partially characterized by chromatographic separation and electrophoresis. The antigen responsible for tumor rejection activity had a molecular w...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1977-09, Vol.37 (9), p.3406
Hauptverfasser:	Natori, T, Law, L W, Appella, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Neoplasm - administration & dosage Antigens, Neoplasm - isolation & purification beta 2-Microglobulin - analysis Chromatography, Affinity Chromatography, Gel Detergents Electrophoresis, Polyacrylamide Gel Epitopes Female Graft Rejection Histocompatibility Antigens - isolation & purification Methylcholanthrene Mice Mice, Inbred BALB C Molecular Weight Neoplasm Transplantation Radioimmunoassay Sarcoma, Experimental - chemically induced Sarcoma, Experimental - immunology Solubility Transplantation, Isogeneic
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