Quantitative neoplastic transformation of C3H/10T1/2 fibroblasts: dependence upon the size of the initiated cell colony at confluence

The efficiency of transformation of C3H/10T1/2 fibroblasts by chemical or physical carcinogens varies inversely with the seeding density of the cells. Colony size at confluence, accumulated cell generations, and epigenetic events independent of seeding density have been proposed to explain this vari...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1983-09, Vol.43 (9), p.4062
Hauptverfasser:	Mordan, L J, Martner, J E, Bertram, J S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Adhesion Cell Cycle Cell Survival Cell Transformation, Neoplastic Cells, Cultured Kinetics Methylcholanthrene - toxicity Mice Mice, Inbred C3H Mice, Nude
Online-Zugang:	Volltext
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