Prenatal Exposure to Diethylstilbestrol: Ovarian-Independent Growth of Mammary Tumors Induced 7,12-Dimethylbenz[a]anthracene

The effects of ovariectomy on the growth of 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumors were investigated after rats had been exposed prenatally to diethylstilbestrol (DES). Pregnant rats were inoculated with either DES (total dose: 1.2 μg) in sesame oil or with the vehicle alone on...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1981-04, Vol.66 (4), p.649-652
Hauptverfasser:	Boylan, Elizabeth S., Calhoon, Robert E.
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene Adenocarcinoma - chemically induced Adenofibroma - chemically induced Animals Castration Diethylstilbestrol Female Mammary Neoplasms, Experimental - chemically induced Mammary Neoplasms, Experimental - pathology Maternal-Fetal Exchange Ovary - physiology Pregnancy Prognosis Rats Time Factors
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