Treatment of Perennial Allergic Rhinitis by Local Hyperthermia
Ninety-five patients with documented perennial allergic rhinitis have been treated with local hyperthermia of the nasal passages in a randomized double-blind trial. The treatment consisted of one series of three 30-min insufflations of humidified air at 43 degrees C at a 2-hr interval. In the active...
Gespeichert in:
| Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 1982-08, Vol.79 (15), p.4766-4769 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 4769 |
|---|---|
| container_issue | 15 |
| container_start_page | 4766 |
| container_title | Proceedings of the National Academy of Sciences - PNAS |
| container_volume | 79 |
| creator | Yerushalmi, Aharon Karman, Sergiu Lwoff, Andre |
| description | Ninety-five patients with documented perennial allergic rhinitis have been treated with local hyperthermia of the nasal passages in a randomized double-blind trial. The treatment consisted of one series of three 30-min insufflations of humidified air at 43 degrees C at a 2-hr interval. In the active treatment group, 75% (P < 0.00003) and 68% (P < 0.00001) of the patients were free of symptoms 1 week and 1 month, respectively, after treatment, compared with a 28% and 17% response in the placebo group. We conclude that local hyperthermia is effective in the treatment of perennial allergic rhinitis. |
| doi_str_mv | 10.1073/pnas.79.15.4766 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_pubme</sourceid><recordid>TN_cdi_pubmed_primary_6750609</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>12269</jstor_id><sourcerecordid>12269</sourcerecordid><originalsourceid>FETCH-LOGICAL-c556t-af2cdd1762be7494e7fcb7573bbdf99cf304cf5d935013ef45a55c3e3b9b63bb3</originalsourceid><addsrcrecordid>eNp9kM1PGzEQxa2qiAbac6VKrfYEpw32-is-gIQQlEqRWlX0bHm9Y2Lk3Q22g8h_j6MEKBdOc3i_N_PmIfSV4CnBkp4sB5OmUk0JnzIpxAc0IViRWjCFP6IJxo2sZ6xhn9BBSncYY8VneB_tC8mxwGqCzm4imNzDkKvRVX8gwjB4E6rzECDeelv9XfjBZ5-qdl3NR1uk6_USYl5A7L35jPacCQm-7OYh-nd1eXNxXc9___x1cT6vLeci18Y1tuuIFE0LkikG0tlWcknbtnNKWUcxs453inJMKDjGDeeWAm1VKwpED9Hpdu9y1fbQ2ZI3mqCX0fcmrvVovH6rDH6hb8cHTVl5dVb8Rzt_HO9XkLLufbIQghlgXCUtWdMoyUgBT7agjWNKEdzLDYL1pnG9aVxLpQnXm8aL4_v_0V74XcVFP97pG-Oz-rpAu1UIGR5zIX-8Sxbg2xa4S3mMr8maRij6BNVNn7E</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>74229741</pqid></control><display><type>article</type><title>Treatment of Perennial Allergic Rhinitis by Local Hyperthermia</title><source>MEDLINE</source><source>JSTOR Archive Collection A-Z Listing</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>Free Full-Text Journals in Chemistry</source><creator>Yerushalmi, Aharon ; Karman, Sergiu ; Lwoff, Andre</creator><creatorcontrib>Yerushalmi, Aharon ; Karman, Sergiu ; Lwoff, Andre</creatorcontrib><description>Ninety-five patients with documented perennial allergic rhinitis have been treated with local hyperthermia of the nasal passages in a randomized double-blind trial. The treatment consisted of one series of three 30-min insufflations of humidified air at 43 degrees C at a 2-hr interval. In the active treatment group, 75% (P < 0.00003) and 68% (P < 0.00001) of the patients were free of symptoms 1 week and 1 month, respectively, after treatment, compared with a 28% and 17% response in the placebo group. We conclude that local hyperthermia is effective in the treatment of perennial allergic rhinitis.</description><identifier>ISSN: 0027-8424</identifier><identifier>EISSN: 1091-6490</identifier><identifier>DOI: 10.1073/pnas.79.15.4766</identifier><identifier>PMID: 6750609</identifier><language>eng</language><publisher>United States: National Academy of Sciences of the United States of America</publisher><subject>Adolescent ; Adult ; Aged ; Allergies ; Allergy tests ; Child ; Child, Preschool ; Clinical Trials as Topic ; Double-Blind Method ; Female ; Follow-Up Studies ; Hot Temperature ; Humans ; Induced hyperthermia ; Inhalants ; Itching ; Male ; Middle Aged ; Perennial allergic rhinitis ; Placebos ; Pollen ; Rhinitis, Allergic, Perennial - therapy ; Sneezing ; Symptoms</subject><ispartof>Proceedings of the National Academy of Sciences - PNAS, 1982-08, Vol.79 (15), p.4766-4769</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c556t-af2cdd1762be7494e7fcb7573bbdf99cf304cf5d935013ef45a55c3e3b9b63bb3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://www.pnas.org/content/79/15.cover.gif</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/12269$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/12269$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,727,780,784,803,885,27924,27925,53791,53793,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6750609$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yerushalmi, Aharon</creatorcontrib><creatorcontrib>Karman, Sergiu</creatorcontrib><creatorcontrib>Lwoff, Andre</creatorcontrib><title>Treatment of Perennial Allergic Rhinitis by Local Hyperthermia</title><title>Proceedings of the National Academy of Sciences - PNAS</title><addtitle>Proc Natl Acad Sci U S A</addtitle><description>Ninety-five patients with documented perennial allergic rhinitis have been treated with local hyperthermia of the nasal passages in a randomized double-blind trial. The treatment consisted of one series of three 30-min insufflations of humidified air at 43 degrees C at a 2-hr interval. In the active treatment group, 75% (P < 0.00003) and 68% (P < 0.00001) of the patients were free of symptoms 1 week and 1 month, respectively, after treatment, compared with a 28% and 17% response in the placebo group. We conclude that local hyperthermia is effective in the treatment of perennial allergic rhinitis.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Allergies</subject><subject>Allergy tests</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Clinical Trials as Topic</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hot Temperature</subject><subject>Humans</subject><subject>Induced hyperthermia</subject><subject>Inhalants</subject><subject>Itching</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Perennial allergic rhinitis</subject><subject>Placebos</subject><subject>Pollen</subject><subject>Rhinitis, Allergic, Perennial - therapy</subject><subject>Sneezing</subject><subject>Symptoms</subject><issn>0027-8424</issn><issn>1091-6490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1PGzEQxa2qiAbac6VKrfYEpw32-is-gIQQlEqRWlX0bHm9Y2Lk3Q22g8h_j6MEKBdOc3i_N_PmIfSV4CnBkp4sB5OmUk0JnzIpxAc0IViRWjCFP6IJxo2sZ6xhn9BBSncYY8VneB_tC8mxwGqCzm4imNzDkKvRVX8gwjB4E6rzECDeelv9XfjBZ5-qdl3NR1uk6_USYl5A7L35jPacCQm-7OYh-nd1eXNxXc9___x1cT6vLeci18Y1tuuIFE0LkikG0tlWcknbtnNKWUcxs453inJMKDjGDeeWAm1VKwpED9Hpdu9y1fbQ2ZI3mqCX0fcmrvVovH6rDH6hb8cHTVl5dVb8Rzt_HO9XkLLufbIQghlgXCUtWdMoyUgBT7agjWNKEdzLDYL1pnG9aVxLpQnXm8aL4_v_0V74XcVFP97pG-Oz-rpAu1UIGR5zIX-8Sxbg2xa4S3mMr8maRij6BNVNn7E</recordid><startdate>19820801</startdate><enddate>19820801</enddate><creator>Yerushalmi, Aharon</creator><creator>Karman, Sergiu</creator><creator>Lwoff, Andre</creator><general>National Academy of Sciences of the United States of America</general><general>National Acad Sciences</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19820801</creationdate><title>Treatment of Perennial Allergic Rhinitis by Local Hyperthermia</title><author>Yerushalmi, Aharon ; Karman, Sergiu ; Lwoff, Andre</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c556t-af2cdd1762be7494e7fcb7573bbdf99cf304cf5d935013ef45a55c3e3b9b63bb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Allergies</topic><topic>Allergy tests</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Clinical Trials as Topic</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hot Temperature</topic><topic>Humans</topic><topic>Induced hyperthermia</topic><topic>Inhalants</topic><topic>Itching</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Perennial allergic rhinitis</topic><topic>Placebos</topic><topic>Pollen</topic><topic>Rhinitis, Allergic, Perennial - therapy</topic><topic>Sneezing</topic><topic>Symptoms</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yerushalmi, Aharon</creatorcontrib><creatorcontrib>Karman, Sergiu</creatorcontrib><creatorcontrib>Lwoff, Andre</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yerushalmi, Aharon</au><au>Karman, Sergiu</au><au>Lwoff, Andre</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of Perennial Allergic Rhinitis by Local Hyperthermia</atitle><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle><addtitle>Proc Natl Acad Sci U S A</addtitle><date>1982-08-01</date><risdate>1982</risdate><volume>79</volume><issue>15</issue><spage>4766</spage><epage>4769</epage><pages>4766-4769</pages><issn>0027-8424</issn><eissn>1091-6490</eissn><abstract>Ninety-five patients with documented perennial allergic rhinitis have been treated with local hyperthermia of the nasal passages in a randomized double-blind trial. The treatment consisted of one series of three 30-min insufflations of humidified air at 43 degrees C at a 2-hr interval. In the active treatment group, 75% (P < 0.00003) and 68% (P < 0.00001) of the patients were free of symptoms 1 week and 1 month, respectively, after treatment, compared with a 28% and 17% response in the placebo group. We conclude that local hyperthermia is effective in the treatment of perennial allergic rhinitis.</abstract><cop>United States</cop><pub>National Academy of Sciences of the United States of America</pub><pmid>6750609</pmid><doi>10.1073/pnas.79.15.4766</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0027-8424 |
| ispartof | Proceedings of the National Academy of Sciences - PNAS, 1982-08, Vol.79 (15), p.4766-4769 |
| issn | 0027-8424 1091-6490 |
| language | eng |
| recordid | cdi_pubmed_primary_6750609 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | Adolescent Adult Aged Allergies Allergy tests Child Child, Preschool Clinical Trials as Topic Double-Blind Method Female Follow-Up Studies Hot Temperature Humans Induced hyperthermia Inhalants Itching Male Middle Aged Perennial allergic rhinitis Placebos Pollen Rhinitis, Allergic, Perennial - therapy Sneezing Symptoms |
| title | Treatment of Perennial Allergic Rhinitis by Local Hyperthermia |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-30T12%3A48%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Treatment%20of%20Perennial%20Allergic%20Rhinitis%20by%20Local%20Hyperthermia&rft.jtitle=Proceedings%20of%20the%20National%20Academy%20of%20Sciences%20-%20PNAS&rft.au=Yerushalmi,%20Aharon&rft.date=1982-08-01&rft.volume=79&rft.issue=15&rft.spage=4766&rft.epage=4769&rft.pages=4766-4769&rft.issn=0027-8424&rft.eissn=1091-6490&rft_id=info:doi/10.1073/pnas.79.15.4766&rft_dat=%3Cjstor_pubme%3E12269%3C/jstor_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=74229741&rft_id=info:pmid/6750609&rft_jstor_id=12269&rfr_iscdi=true |