Resistance to 5-fluorouracil associated with increased cytidine triphosphate levels in V79 Chinese hamster cells

Clones stably resistant to the toxic effects of 5-fluorouracil have been isolated from V79.5 Chinese hamster fibroblast cells by a single-step selection procedure. The 5-fluorouracil-resistant lines were found to (a) have an auxotrophic requirement when grown in dialyzed fetal calf serum that was sa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1984-08, Vol.44 (8), p.3371-3376
1. Verfasser:	KAUFMAN, E. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Carbon-Nitrogen Ligases Cell Line Cricetinae Cricetulus Cytidine Triphosphate - metabolism Cytosine Nucleotides - metabolism Deoxyribonucleotides - metabolism Drug Resistance Fluorouracil - metabolism Fluorouracil - toxicity General aspects Kinetics Ligases - metabolism Lung Medical sciences Pharmacology. Drug treatments Ribonucleotides - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!