Combined effects of captopril and the diuretic trichloromethiazide on blood pressure in patients with essential hypertension

Various doses (5, 12.5 and 25 mg) of angiotensin I converting enzyme inhibor (captopril) were administered orally alone and following pretreatment with 2 mg of trichloromethiazide (TH) in patients with essential hypertension. The time courses of mean blood pressure (MBP), plasma renin activity (PRA)...

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Veröffentlicht in:	Nihon Jinzo Gakkai shi 1984, Vol.26(9), pp.1251-1258
Hauptverfasser:	IZUMI, YOICHI, HONDA, MASANOBU, HATANO, MICHINOBU, KAWAHARA, YUKINORI
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult angiotensin l converting enzyme Blood Pressure - drug effects captopril Captopril - therapeutic use Dose-Response Relationship, Drug Drug Interactions Female Humans Hypertension - drug therapy Kinetics Male Middle Aged PRA Proline - analogs & derivatives Renin - blood Trichlormethiazide - therapeutic use trichloromethiazide
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