Mutants of Sindbis virus: I. Isolation and partial characterization of 89 new temperature-sensitive mutants

More than 100 new temperature-sensitive mutants of Sindbis virus have been isolated, following mutagenesis with nitrous acid, N-methyl- N′-nitro- N-nitrosoguanidine, 5-azacytidine, and 5-fluorouridine. Thirty-six of these mutants synthesize at least 60% as much RNA at the nonpermissive temperature a...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1976-10, Vol.74 (1), p.154-168
Hauptverfasser:	Strauss, Ellen G., Lenches, Edith M., Strauss, James H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Azacitidine Fluorouracil Genes Genetic Complementation Test Methylnitronitrosoguanidine Mutagens Mutation Nitrites RNA, Viral - biosynthesis Sindbis Virus - metabolism Temperature Viral Proteins - biosynthesis
Online-Zugang:	Volltext
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