Extraocular muscle involvement in Wegener's granulomatosis
A 44-year-old man with Wegener's granulomatosis involving the upper and lower respiratory tracts developed a diplopia with involvement of three extraocular muscles of one eye and one extraocular muscle of the other eye. The ocular and orbital examinations were otherwise normal, as were computer...
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| Veröffentlicht in: | Journal of clinical neuro-ophthalmology 1983-09, Vol.3 (3), p.163-168 |
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| container_title | Journal of clinical neuro-ophthalmology |
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| creator | PINCHOFF, B. S SPAHLINGER, D. A BERGSTROM, T. J SANDALL, G. S |
| description | A 44-year-old man with Wegener's granulomatosis involving the upper and lower respiratory tracts developed a diplopia with involvement of three extraocular muscles of one eye and one extraocular muscle of the other eye. The ocular and orbital examinations were otherwise normal, as were computerized tomography (CT) scans of the brain and orbits. The patient was treated with systemic Cytoxan and Prednisone and the respiratory and extraocular muscle abnormalities cleared within 1 month. Because of the bilateral extraocular muscle involvement, the absence of central nervous system or orbital findings, and the rapid and complete resolution after Cytoxan and Prednisone therapy, a diffuse vasculitis affecting the extraocular muscles was implicated as the etiology of the diplopia. |
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J ; SANDALL, G. S</creator><creatorcontrib>PINCHOFF, B. S ; SPAHLINGER, D. A ; BERGSTROM, T. J ; SANDALL, G. S</creatorcontrib><description>A 44-year-old man with Wegener's granulomatosis involving the upper and lower respiratory tracts developed a diplopia with involvement of three extraocular muscles of one eye and one extraocular muscle of the other eye. The ocular and orbital examinations were otherwise normal, as were computerized tomography (CT) scans of the brain and orbits. The patient was treated with systemic Cytoxan and Prednisone and the respiratory and extraocular muscle abnormalities cleared within 1 month. Because of the bilateral extraocular muscle involvement, the absence of central nervous system or orbital findings, and the rapid and complete resolution after Cytoxan and Prednisone therapy, a diffuse vasculitis affecting the extraocular muscles was implicated as the etiology of the diplopia.</description><identifier>ISSN: 0272-846X</identifier><identifier>PMID: 6226714</identifier><identifier>CODEN: JCNODL</identifier><language>eng</language><publisher>New York, NY: Raven Press</publisher><subject>Adult ; Biological and medical sciences ; Cyclophosphamide - administration & dosage ; Diplopia - etiology ; Eye - physiopathology ; Eye Movements ; Granulomatosis with Polyangiitis - complications ; Granulomatosis with Polyangiitis - drug therapy ; Granulomatosis with Polyangiitis - physiopathology ; Humans ; Male ; Medical sciences ; Muscles - physiopathology ; Prednisone - administration & dosage ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><ispartof>Journal of clinical neuro-ophthalmology, 1983-09, Vol.3 (3), p.163-168</ispartof><rights>1984 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9335390$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6226714$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>PINCHOFF, B. S</creatorcontrib><creatorcontrib>SPAHLINGER, D. A</creatorcontrib><creatorcontrib>BERGSTROM, T. J</creatorcontrib><creatorcontrib>SANDALL, G. S</creatorcontrib><title>Extraocular muscle involvement in Wegener's granulomatosis</title><title>Journal of clinical neuro-ophthalmology</title><addtitle>J Clin Neuroophthalmol</addtitle><description>A 44-year-old man with Wegener's granulomatosis involving the upper and lower respiratory tracts developed a diplopia with involvement of three extraocular muscles of one eye and one extraocular muscle of the other eye. The ocular and orbital examinations were otherwise normal, as were computerized tomography (CT) scans of the brain and orbits. The patient was treated with systemic Cytoxan and Prednisone and the respiratory and extraocular muscle abnormalities cleared within 1 month. Because of the bilateral extraocular muscle involvement, the absence of central nervous system or orbital findings, and the rapid and complete resolution after Cytoxan and Prednisone therapy, a diffuse vasculitis affecting the extraocular muscles was implicated as the etiology of the diplopia.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cyclophosphamide - administration & dosage</subject><subject>Diplopia - etiology</subject><subject>Eye - physiopathology</subject><subject>Eye Movements</subject><subject>Granulomatosis with Polyangiitis - complications</subject><subject>Granulomatosis with Polyangiitis - drug therapy</subject><subject>Granulomatosis with Polyangiitis - physiopathology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Muscles - physiopathology</subject><subject>Prednisone - administration & dosage</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><issn>0272-846X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9j09Lw0AUxPeg1Fr9CEIOgqfAy74k63qTUq1Q8KLorby8fSmRzR92k6Lf3oLB0wz8hmHmTC1BG53e5-XnhbqM8QsAczR2oRal1qXJ8qV62HyPgXqePIWknSJ7SZru2PujtNKNJ598yEE6CXcxOQTqJt-3NPaxiVfqvCYf5XrWlXp_2rytt-nu9fll_bhLh6yAMXWGM5drB4hgNRdkHTJiza4QcVDZkixwWSHryhS5ITHAUBMLWNAouFI3f73DVLXi9kNoWgo_-_nDid_OnCKTr08juYn_MYtYoAX8BRCgT6Y</recordid><startdate>198309</startdate><enddate>198309</enddate><creator>PINCHOFF, B. S</creator><creator>SPAHLINGER, D. A</creator><creator>BERGSTROM, T. J</creator><creator>SANDALL, G. S</creator><general>Raven Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>198309</creationdate><title>Extraocular muscle involvement in Wegener's granulomatosis</title><author>PINCHOFF, B. S ; SPAHLINGER, D. A ; BERGSTROM, T. J ; SANDALL, G. 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Vasculitis</topic><toplevel>online_resources</toplevel><creatorcontrib>PINCHOFF, B. S</creatorcontrib><creatorcontrib>SPAHLINGER, D. A</creatorcontrib><creatorcontrib>BERGSTROM, T. J</creatorcontrib><creatorcontrib>SANDALL, G. S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Journal of clinical neuro-ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PINCHOFF, B. S</au><au>SPAHLINGER, D. A</au><au>BERGSTROM, T. J</au><au>SANDALL, G. S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Extraocular muscle involvement in Wegener's granulomatosis</atitle><jtitle>Journal of clinical neuro-ophthalmology</jtitle><addtitle>J Clin Neuroophthalmol</addtitle><date>1983-09</date><risdate>1983</risdate><volume>3</volume><issue>3</issue><spage>163</spage><epage>168</epage><pages>163-168</pages><issn>0272-846X</issn><coden>JCNODL</coden><abstract>A 44-year-old man with Wegener's granulomatosis involving the upper and lower respiratory tracts developed a diplopia with involvement of three extraocular muscles of one eye and one extraocular muscle of the other eye. The ocular and orbital examinations were otherwise normal, as were computerized tomography (CT) scans of the brain and orbits. The patient was treated with systemic Cytoxan and Prednisone and the respiratory and extraocular muscle abnormalities cleared within 1 month. Because of the bilateral extraocular muscle involvement, the absence of central nervous system or orbital findings, and the rapid and complete resolution after Cytoxan and Prednisone therapy, a diffuse vasculitis affecting the extraocular muscles was implicated as the etiology of the diplopia.</abstract><cop>New York, NY</cop><pub>Raven Press</pub><pmid>6226714</pmid><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0272-846X |
| ispartof | Journal of clinical neuro-ophthalmology, 1983-09, Vol.3 (3), p.163-168 |
| issn | 0272-846X |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Biological and medical sciences Cyclophosphamide - administration & dosage Diplopia - etiology Eye - physiopathology Eye Movements Granulomatosis with Polyangiitis - complications Granulomatosis with Polyangiitis - drug therapy Granulomatosis with Polyangiitis - physiopathology Humans Male Medical sciences Muscles - physiopathology Prednisone - administration & dosage Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis |
| title | Extraocular muscle involvement in Wegener's granulomatosis |
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