Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics

A hundred and fifty-two patients who were to undergo major orthopaedic surgery were divided into two groups in order to study the value of dextrans administered as adjuvants to oral anticoagulants in the prevention of deep venous thrombosis. The control group had oral anticoagulants only from the ev...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Acta orthopaedica 1984-01, Vol.55 (3), p.251-253
Hauptverfasser: Swierstra, Bart A., van Oosterhout, Frank J., Ausema, Bert, Bakker, Willem H., van der Pompe, Willem B., Schouten, Hubert J. A.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 253
container_issue 3
container_start_page 251
container_title Acta orthopaedica
container_volume 55
creator Swierstra, Bart A.
van Oosterhout, Frank J.
Ausema, Bert
Bakker, Willem H.
van der Pompe, Willem B.
Schouten, Hubert J. A.
description A hundred and fifty-two patients who were to undergo major orthopaedic surgery were divided into two groups in order to study the value of dextrans administered as adjuvants to oral anticoagulants in the prevention of deep venous thrombosis. The control group had oral anticoagulants only from the evening before the day of operation, aimed at the 15 per cent thrombotest level. The dextran group had peroperative and postoperative dextran infusions as well. Radionuclide venography was used for thrombosis detection. The dextran group had a lower incidence of thrombosis, but more haemorrhagic problems. The incidence of thrombosis was high in both groups.
doi_str_mv 10.3109/17453678408992349
format Article
fullrecord <record><control><sourceid>pubmed_pasca</sourceid><recordid>TN_cdi_pubmed_primary_6204501</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>6204501</sourcerecordid><originalsourceid>FETCH-LOGICAL-c473t-bdcbbd4c36f747dee9ccffc1edc302783d1db9291fb90909c235dc121134befd3</originalsourceid><addsrcrecordid>eNp9kF9LwzAUxYMoU6cfwAchD75WkyZrG_RFhv9gsAf1uSQ3ie1om5G06r69GZsDEUYecnLvOeHeH0IXlFwzSsQNzfmEZXnBSSFEyrg4QCfrWsKyIj3c6Zwfo9MQFoSwggsyQqMsJXxC6Al6nXvZYNn1NTj5MTRRhfjUWJvv3ssOW-fx0ptPEy2uw87iKN0QcF951yoX6oDrWPd95ZbS6BrCGTqysgnmfHuP0fvjw9v0OZnNn16m97MEeM76RGlQSnNgmc15ro0RANYCNRoYSfOCaaqVSAW1SpB4IGUTDTSllHFlrGZjRDf_gncheGPLpa9b6VclJeWaT_mPT8xcbjLLQbVG7xJbILF_te3LALKxEQHUYWcrBCk4Z9F2t7HVXQTUyi_nG132ctU4_5th-6a4_ROvjGz6CqQ35cINvovU9uzwA3PKlPM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Swierstra, Bart A. ; van Oosterhout, Frank J. ; Ausema, Bert ; Bakker, Willem H. ; van der Pompe, Willem B. ; Schouten, Hubert J. A.</creator><creatorcontrib>Swierstra, Bart A. ; van Oosterhout, Frank J. ; Ausema, Bert ; Bakker, Willem H. ; van der Pompe, Willem B. ; Schouten, Hubert J. A.</creatorcontrib><description>A hundred and fifty-two patients who were to undergo major orthopaedic surgery were divided into two groups in order to study the value of dextrans administered as adjuvants to oral anticoagulants in the prevention of deep venous thrombosis. The control group had oral anticoagulants only from the evening before the day of operation, aimed at the 15 per cent thrombotest level. The dextran group had peroperative and postoperative dextran infusions as well. Radionuclide venography was used for thrombosis detection. The dextran group had a lower incidence of thrombosis, but more haemorrhagic problems. The incidence of thrombosis was high in both groups.</description><identifier>ISSN: 1745-3674</identifier><identifier>ISSN: 0001-6470</identifier><identifier>EISSN: 1745-3682</identifier><identifier>DOI: 10.3109/17453678408992349</identifier><identifier>PMID: 6204501</identifier><identifier>CODEN: AOSAAK</identifier><language>eng</language><publisher>Basingstoke: Informa UK Ltd</publisher><subject>Acenocoumarol - adverse effects ; Acenocoumarol - therapeutic use ; Anticoagulants - therapeutic use ; Biological and medical sciences ; Blood. Blood coagulation. Reticuloendothelial system ; Dextrans - adverse effects ; Dextrans - therapeutic use ; Female ; Hemorrhage - chemically induced ; Humans ; Intraoperative Care ; Male ; Medical sciences ; Orthopedics ; Pharmacology. Drug treatments ; Postoperative Care ; Postoperative Complications - etiology ; Postoperative Complications - prevention &amp; control ; Premedication ; Thrombophlebitis - etiology ; Thrombophlebitis - prevention &amp; control</subject><ispartof>Acta orthopaedica, 1984-01, Vol.55 (3), p.251-253</ispartof><rights>1984 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1984</rights><rights>1985 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c473t-bdcbbd4c36f747dee9ccffc1edc302783d1db9291fb90909c235dc121134befd3</citedby><cites>FETCH-LOGICAL-c473t-bdcbbd4c36f747dee9ccffc1edc302783d1db9291fb90909c235dc121134befd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=8908443$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6204501$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Swierstra, Bart A.</creatorcontrib><creatorcontrib>van Oosterhout, Frank J.</creatorcontrib><creatorcontrib>Ausema, Bert</creatorcontrib><creatorcontrib>Bakker, Willem H.</creatorcontrib><creatorcontrib>van der Pompe, Willem B.</creatorcontrib><creatorcontrib>Schouten, Hubert J. A.</creatorcontrib><title>Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics</title><title>Acta orthopaedica</title><addtitle>Acta Orthop Scand</addtitle><description>A hundred and fifty-two patients who were to undergo major orthopaedic surgery were divided into two groups in order to study the value of dextrans administered as adjuvants to oral anticoagulants in the prevention of deep venous thrombosis. The control group had oral anticoagulants only from the evening before the day of operation, aimed at the 15 per cent thrombotest level. The dextran group had peroperative and postoperative dextran infusions as well. Radionuclide venography was used for thrombosis detection. The dextran group had a lower incidence of thrombosis, but more haemorrhagic problems. The incidence of thrombosis was high in both groups.</description><subject>Acenocoumarol - adverse effects</subject><subject>Acenocoumarol - therapeutic use</subject><subject>Anticoagulants - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Blood. Blood coagulation. Reticuloendothelial system</subject><subject>Dextrans - adverse effects</subject><subject>Dextrans - therapeutic use</subject><subject>Female</subject><subject>Hemorrhage - chemically induced</subject><subject>Humans</subject><subject>Intraoperative Care</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Orthopedics</subject><subject>Pharmacology. Drug treatments</subject><subject>Postoperative Care</subject><subject>Postoperative Complications - etiology</subject><subject>Postoperative Complications - prevention &amp; control</subject><subject>Premedication</subject><subject>Thrombophlebitis - etiology</subject><subject>Thrombophlebitis - prevention &amp; control</subject><issn>1745-3674</issn><issn>0001-6470</issn><issn>1745-3682</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF9LwzAUxYMoU6cfwAchD75WkyZrG_RFhv9gsAf1uSQ3ie1om5G06r69GZsDEUYecnLvOeHeH0IXlFwzSsQNzfmEZXnBSSFEyrg4QCfrWsKyIj3c6Zwfo9MQFoSwggsyQqMsJXxC6Al6nXvZYNn1NTj5MTRRhfjUWJvv3ssOW-fx0ptPEy2uw87iKN0QcF951yoX6oDrWPd95ZbS6BrCGTqysgnmfHuP0fvjw9v0OZnNn16m97MEeM76RGlQSnNgmc15ro0RANYCNRoYSfOCaaqVSAW1SpB4IGUTDTSllHFlrGZjRDf_gncheGPLpa9b6VclJeWaT_mPT8xcbjLLQbVG7xJbILF_te3LALKxEQHUYWcrBCk4Z9F2t7HVXQTUyi_nG132ctU4_5th-6a4_ROvjGz6CqQ35cINvovU9uzwA3PKlPM</recordid><startdate>19840101</startdate><enddate>19840101</enddate><creator>Swierstra, Bart A.</creator><creator>van Oosterhout, Frank J.</creator><creator>Ausema, Bert</creator><creator>Bakker, Willem H.</creator><creator>van der Pompe, Willem B.</creator><creator>Schouten, Hubert J. A.</creator><general>Informa UK Ltd</general><general>Taylor &amp; Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19840101</creationdate><title>Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics</title><author>Swierstra, Bart A. ; van Oosterhout, Frank J. ; Ausema, Bert ; Bakker, Willem H. ; van der Pompe, Willem B. ; Schouten, Hubert J. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c473t-bdcbbd4c36f747dee9ccffc1edc302783d1db9291fb90909c235dc121134befd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Acenocoumarol - adverse effects</topic><topic>Acenocoumarol - therapeutic use</topic><topic>Anticoagulants - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Blood. Blood coagulation. Reticuloendothelial system</topic><topic>Dextrans - adverse effects</topic><topic>Dextrans - therapeutic use</topic><topic>Female</topic><topic>Hemorrhage - chemically induced</topic><topic>Humans</topic><topic>Intraoperative Care</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Orthopedics</topic><topic>Pharmacology. Drug treatments</topic><topic>Postoperative Care</topic><topic>Postoperative Complications - etiology</topic><topic>Postoperative Complications - prevention &amp; control</topic><topic>Premedication</topic><topic>Thrombophlebitis - etiology</topic><topic>Thrombophlebitis - prevention &amp; control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Swierstra, Bart A.</creatorcontrib><creatorcontrib>van Oosterhout, Frank J.</creatorcontrib><creatorcontrib>Ausema, Bert</creatorcontrib><creatorcontrib>Bakker, Willem H.</creatorcontrib><creatorcontrib>van der Pompe, Willem B.</creatorcontrib><creatorcontrib>Schouten, Hubert J. A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Acta orthopaedica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Swierstra, Bart A.</au><au>van Oosterhout, Frank J.</au><au>Ausema, Bert</au><au>Bakker, Willem H.</au><au>van der Pompe, Willem B.</au><au>Schouten, Hubert J. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics</atitle><jtitle>Acta orthopaedica</jtitle><addtitle>Acta Orthop Scand</addtitle><date>1984-01-01</date><risdate>1984</risdate><volume>55</volume><issue>3</issue><spage>251</spage><epage>253</epage><pages>251-253</pages><issn>1745-3674</issn><issn>0001-6470</issn><eissn>1745-3682</eissn><coden>AOSAAK</coden><abstract>A hundred and fifty-two patients who were to undergo major orthopaedic surgery were divided into two groups in order to study the value of dextrans administered as adjuvants to oral anticoagulants in the prevention of deep venous thrombosis. The control group had oral anticoagulants only from the evening before the day of operation, aimed at the 15 per cent thrombotest level. The dextran group had peroperative and postoperative dextran infusions as well. Radionuclide venography was used for thrombosis detection. The dextran group had a lower incidence of thrombosis, but more haemorrhagic problems. The incidence of thrombosis was high in both groups.</abstract><cop>Basingstoke</cop><pub>Informa UK Ltd</pub><pmid>6204501</pmid><doi>10.3109/17453678408992349</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1745-3674
ispartof Acta orthopaedica, 1984-01, Vol.55 (3), p.251-253
issn 1745-3674
0001-6470
1745-3682
language eng
recordid cdi_pubmed_primary_6204501
source MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Acenocoumarol - adverse effects
Acenocoumarol - therapeutic use
Anticoagulants - therapeutic use
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Dextrans - adverse effects
Dextrans - therapeutic use
Female
Hemorrhage - chemically induced
Humans
Intraoperative Care
Male
Medical sciences
Orthopedics
Pharmacology. Drug treatments
Postoperative Care
Postoperative Complications - etiology
Postoperative Complications - prevention & control
Premedication
Thrombophlebitis - etiology
Thrombophlebitis - prevention & control
title Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T00%3A59%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_pasca&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Oral%20anticoagulants%20and%20dextran%20for%20prevention%20of%20venous%20thrombosis%20in%20orthopaedics&rft.jtitle=Acta%20orthopaedica&rft.au=Swierstra,%20Bart%20A.&rft.date=1984-01-01&rft.volume=55&rft.issue=3&rft.spage=251&rft.epage=253&rft.pages=251-253&rft.issn=1745-3674&rft.eissn=1745-3682&rft.coden=AOSAAK&rft_id=info:doi/10.3109/17453678408992349&rft_dat=%3Cpubmed_pasca%3E6204501%3C/pubmed_pasca%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/6204501&rfr_iscdi=true