Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics
A hundred and fifty-two patients who were to undergo major orthopaedic surgery were divided into two groups in order to study the value of dextrans administered as adjuvants to oral anticoagulants in the prevention of deep venous thrombosis. The control group had oral anticoagulants only from the ev...
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Veröffentlicht in: | Acta orthopaedica 1984-01, Vol.55 (3), p.251-253 |
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container_title | Acta orthopaedica |
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creator | Swierstra, Bart A. van Oosterhout, Frank J. Ausema, Bert Bakker, Willem H. van der Pompe, Willem B. Schouten, Hubert J. A. |
description | A hundred and fifty-two patients who were to undergo major orthopaedic surgery were divided into two groups in order to study the value of dextrans administered as adjuvants to oral anticoagulants in the prevention of deep venous thrombosis.
The control group had oral anticoagulants only from the evening before the day of operation, aimed at the 15 per cent thrombotest level. The dextran group had peroperative and postoperative dextran infusions as well. Radionuclide venography was used for thrombosis detection. The dextran group had a lower incidence of thrombosis, but more haemorrhagic problems. The incidence of thrombosis was high in both groups. |
doi_str_mv | 10.3109/17453678408992349 |
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The control group had oral anticoagulants only from the evening before the day of operation, aimed at the 15 per cent thrombotest level. The dextran group had peroperative and postoperative dextran infusions as well. Radionuclide venography was used for thrombosis detection. The dextran group had a lower incidence of thrombosis, but more haemorrhagic problems. The incidence of thrombosis was high in both groups.</description><identifier>ISSN: 1745-3674</identifier><identifier>ISSN: 0001-6470</identifier><identifier>EISSN: 1745-3682</identifier><identifier>DOI: 10.3109/17453678408992349</identifier><identifier>PMID: 6204501</identifier><identifier>CODEN: AOSAAK</identifier><language>eng</language><publisher>Basingstoke: Informa UK Ltd</publisher><subject>Acenocoumarol - adverse effects ; Acenocoumarol - therapeutic use ; Anticoagulants - therapeutic use ; Biological and medical sciences ; Blood. Blood coagulation. Reticuloendothelial system ; Dextrans - adverse effects ; Dextrans - therapeutic use ; Female ; Hemorrhage - chemically induced ; Humans ; Intraoperative Care ; Male ; Medical sciences ; Orthopedics ; Pharmacology. Drug treatments ; Postoperative Care ; Postoperative Complications - etiology ; Postoperative Complications - prevention & control ; Premedication ; Thrombophlebitis - etiology ; Thrombophlebitis - prevention & control</subject><ispartof>Acta orthopaedica, 1984-01, Vol.55 (3), p.251-253</ispartof><rights>1984 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1984</rights><rights>1985 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c473t-bdcbbd4c36f747dee9ccffc1edc302783d1db9291fb90909c235dc121134befd3</citedby><cites>FETCH-LOGICAL-c473t-bdcbbd4c36f747dee9ccffc1edc302783d1db9291fb90909c235dc121134befd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8908443$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6204501$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Swierstra, Bart A.</creatorcontrib><creatorcontrib>van Oosterhout, Frank J.</creatorcontrib><creatorcontrib>Ausema, Bert</creatorcontrib><creatorcontrib>Bakker, Willem H.</creatorcontrib><creatorcontrib>van der Pompe, Willem B.</creatorcontrib><creatorcontrib>Schouten, Hubert J. A.</creatorcontrib><title>Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics</title><title>Acta orthopaedica</title><addtitle>Acta Orthop Scand</addtitle><description>A hundred and fifty-two patients who were to undergo major orthopaedic surgery were divided into two groups in order to study the value of dextrans administered as adjuvants to oral anticoagulants in the prevention of deep venous thrombosis.
The control group had oral anticoagulants only from the evening before the day of operation, aimed at the 15 per cent thrombotest level. The dextran group had peroperative and postoperative dextran infusions as well. Radionuclide venography was used for thrombosis detection. The dextran group had a lower incidence of thrombosis, but more haemorrhagic problems. The incidence of thrombosis was high in both groups.</description><subject>Acenocoumarol - adverse effects</subject><subject>Acenocoumarol - therapeutic use</subject><subject>Anticoagulants - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Blood. Blood coagulation. Reticuloendothelial system</subject><subject>Dextrans - adverse effects</subject><subject>Dextrans - therapeutic use</subject><subject>Female</subject><subject>Hemorrhage - chemically induced</subject><subject>Humans</subject><subject>Intraoperative Care</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Orthopedics</subject><subject>Pharmacology. Drug treatments</subject><subject>Postoperative Care</subject><subject>Postoperative Complications - etiology</subject><subject>Postoperative Complications - prevention & control</subject><subject>Premedication</subject><subject>Thrombophlebitis - etiology</subject><subject>Thrombophlebitis - prevention & control</subject><issn>1745-3674</issn><issn>0001-6470</issn><issn>1745-3682</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF9LwzAUxYMoU6cfwAchD75WkyZrG_RFhv9gsAf1uSQ3ie1om5G06r69GZsDEUYecnLvOeHeH0IXlFwzSsQNzfmEZXnBSSFEyrg4QCfrWsKyIj3c6Zwfo9MQFoSwggsyQqMsJXxC6Al6nXvZYNn1NTj5MTRRhfjUWJvv3ssOW-fx0ptPEy2uw87iKN0QcF951yoX6oDrWPd95ZbS6BrCGTqysgnmfHuP0fvjw9v0OZnNn16m97MEeM76RGlQSnNgmc15ro0RANYCNRoYSfOCaaqVSAW1SpB4IGUTDTSllHFlrGZjRDf_gncheGPLpa9b6VclJeWaT_mPT8xcbjLLQbVG7xJbILF_te3LALKxEQHUYWcrBCk4Z9F2t7HVXQTUyi_nG132ctU4_5th-6a4_ROvjGz6CqQ35cINvovU9uzwA3PKlPM</recordid><startdate>19840101</startdate><enddate>19840101</enddate><creator>Swierstra, Bart A.</creator><creator>van Oosterhout, Frank J.</creator><creator>Ausema, Bert</creator><creator>Bakker, Willem H.</creator><creator>van der Pompe, Willem B.</creator><creator>Schouten, Hubert J. A.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19840101</creationdate><title>Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics</title><author>Swierstra, Bart A. ; van Oosterhout, Frank J. ; Ausema, Bert ; Bakker, Willem H. ; van der Pompe, Willem B. ; Schouten, Hubert J. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c473t-bdcbbd4c36f747dee9ccffc1edc302783d1db9291fb90909c235dc121134befd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Acenocoumarol - adverse effects</topic><topic>Acenocoumarol - therapeutic use</topic><topic>Anticoagulants - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Blood. Blood coagulation. Reticuloendothelial system</topic><topic>Dextrans - adverse effects</topic><topic>Dextrans - therapeutic use</topic><topic>Female</topic><topic>Hemorrhage - chemically induced</topic><topic>Humans</topic><topic>Intraoperative Care</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Orthopedics</topic><topic>Pharmacology. Drug treatments</topic><topic>Postoperative Care</topic><topic>Postoperative Complications - etiology</topic><topic>Postoperative Complications - prevention & control</topic><topic>Premedication</topic><topic>Thrombophlebitis - etiology</topic><topic>Thrombophlebitis - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Swierstra, Bart A.</creatorcontrib><creatorcontrib>van Oosterhout, Frank J.</creatorcontrib><creatorcontrib>Ausema, Bert</creatorcontrib><creatorcontrib>Bakker, Willem H.</creatorcontrib><creatorcontrib>van der Pompe, Willem B.</creatorcontrib><creatorcontrib>Schouten, Hubert J. A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Acta orthopaedica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Swierstra, Bart A.</au><au>van Oosterhout, Frank J.</au><au>Ausema, Bert</au><au>Bakker, Willem H.</au><au>van der Pompe, Willem B.</au><au>Schouten, Hubert J. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics</atitle><jtitle>Acta orthopaedica</jtitle><addtitle>Acta Orthop Scand</addtitle><date>1984-01-01</date><risdate>1984</risdate><volume>55</volume><issue>3</issue><spage>251</spage><epage>253</epage><pages>251-253</pages><issn>1745-3674</issn><issn>0001-6470</issn><eissn>1745-3682</eissn><coden>AOSAAK</coden><abstract>A hundred and fifty-two patients who were to undergo major orthopaedic surgery were divided into two groups in order to study the value of dextrans administered as adjuvants to oral anticoagulants in the prevention of deep venous thrombosis.
The control group had oral anticoagulants only from the evening before the day of operation, aimed at the 15 per cent thrombotest level. The dextran group had peroperative and postoperative dextran infusions as well. Radionuclide venography was used for thrombosis detection. The dextran group had a lower incidence of thrombosis, but more haemorrhagic problems. The incidence of thrombosis was high in both groups.</abstract><cop>Basingstoke</cop><pub>Informa UK Ltd</pub><pmid>6204501</pmid><doi>10.3109/17453678408992349</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Acenocoumarol - adverse effects Acenocoumarol - therapeutic use Anticoagulants - therapeutic use Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Dextrans - adverse effects Dextrans - therapeutic use Female Hemorrhage - chemically induced Humans Intraoperative Care Male Medical sciences Orthopedics Pharmacology. Drug treatments Postoperative Care Postoperative Complications - etiology Postoperative Complications - prevention & control Premedication Thrombophlebitis - etiology Thrombophlebitis - prevention & control |
title | Oral anticoagulants and dextran for prevention of venous thrombosis in orthopaedics |
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