Potentiation of histamine-induced itch and flare responses in human skin by the enkephalin analogue FK-33-824, beta-endorphin and morphine

The effect of various opioid or putative neurotransmitter peptides on histamine-induced itch and flare responses was studied in humans after intradermal injection. Significant enhancement of the histamine responses was induced by the stable methionine-enkephalin analogue FK 33-824, beta-endorphin an...

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Veröffentlicht in:	Archives of dermatological research 1982-01, Vol.274 (1-2), p.29
Hauptverfasser:	Fjellner, B, Hägermark, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult beta-Endorphin D-Ala,MePhe,Met-ol-enkephalin Dinoprostone Drug Synergism Endorphins - pharmacology Enkephalin, Methionine - analogs & derivatives Enkephalin, Methionine - pharmacology Female Histamine - pharmacology Humans Indomethacin - pharmacology Male Middle Aged Morphine - pharmacology Naloxone - pharmacology Prostaglandins E - pharmacology Pruritus - chemically induced Skin - drug effects Substance P - pharmacology Vasoactive Intestinal Peptide - pharmacology
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