KINETICS OF PRENEOPLASTIC EPITHELIA OF THE INTESTINAL MUCOSA INDUCED IN BUFFALO RATS BY ORAL ADMINISTRATION OF N, N'-2, 7-FLUORENYLENEBISACETAMIDE

A diet containing 0.025% of N, N'-2, 7-fluorenylenebisacetamide (2, 7-FAA) was administered orally to 18 Buffalo rats for 3 months and to 21 rats for 5 months which corresponded to non-neoplastic stage and preneoplastic stage of carcinogenesis of the intestinal mucosa, respectively. The mitotic...

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Veröffentlicht in:	GANN Japanese Journal of Cancer Research 1977/12/31, Vol.68(6), pp.805-811
Hauptverfasser:	YAMADA, Seiji, ITO, Masao, NAGAYO, Takeo, OKUMURA, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Acetylaminofluorene - administration & dosage 2-Acetylaminofluorene - analogs & derivatives Administration, Oral Animals Epithelium - drug effects Epithelium - pathology Female Fluorenes - administration & dosage Intestinal Mucosa - drug effects Intestinal Mucosa - pathology Intestinal Neoplasms - chemically induced Intestinal Neoplasms - pathology Intestinal tumor Mitotic Index N, N'-2, 7-Fluorenylenebisacetamide Precancerous Conditions - chemically induced Precancerous Conditions - pathology Preneoplastic stage Rats Thymidine - metabolism
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