Cytokinins: Development of a Potent Antagonist
A systematic search has resulted in the synthesis of a class of cytokinin antimetabolites. The development and biological properties of the anticytokinins are discussed in terms of one member of the class, 3-methyl - 7 - (3 - methylbutylamino)pyrazolo[4,3 - d]- pyrimidine.
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Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 1971-10, Vol.68 (10), p.2608-2610 |
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container_title | Proceedings of the National Academy of Sciences - PNAS |
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creator | Hecht, Sidney M. Bock, Robert M. Schmitz, Ruth Y. Skoog, Folke Leonard, Nelson J. |
description | A systematic search has resulted in the synthesis of a class of cytokinin antimetabolites. The development and biological properties of the anticytokinins are discussed in terms of one member of the class, 3-methyl - 7 - (3 - methylbutylamino)pyrazolo[4,3 - d]- pyrimidine. |
doi_str_mv | 10.1073/pnas.68.10.2608 |
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The development and biological properties of the anticytokinins are discussed in terms of one member of the class, 3-methyl - 7 - (3 - methylbutylamino)pyrazolo[4,3 - d]- pyrimidine.</description><identifier>ISSN: 0027-8424</identifier><identifier>EISSN: 1091-6490</identifier><identifier>DOI: 10.1073/pnas.68.10.2608</identifier><identifier>PMID: 5289891</identifier><language>eng</language><publisher>United States: National Academy of Sciences of the United States of America</publisher><subject>Antimetabolites - pharmacology ; Biochemistry ; Biological Sciences: Biochemistry ; Butylamines - pharmacology ; Callus ; Cytokinins ; Kinins - antagonists & inhibitors ; Nicotiana - drug effects ; Plant Growth Regulators - antagonists & inhibitors ; Plants ; Plants, Toxic ; Pyrazoles - pharmacology ; Pyrimidines - pharmacology ; Research grants</subject><ispartof>Proceedings of the National Academy of Sciences - PNAS, 1971-10, Vol.68 (10), p.2608-2610</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c461t-7ad3956438551862287b0c6672245707452fed103b7b2a861cba6be37ac366d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://www.pnas.org/content/68/10.cover.gif</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/61100$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/61100$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,727,780,784,803,885,27924,27925,53791,53793,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5289891$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hecht, Sidney M.</creatorcontrib><creatorcontrib>Bock, Robert M.</creatorcontrib><creatorcontrib>Schmitz, Ruth Y.</creatorcontrib><creatorcontrib>Skoog, Folke</creatorcontrib><creatorcontrib>Leonard, Nelson J.</creatorcontrib><title>Cytokinins: Development of a Potent Antagonist</title><title>Proceedings of the National Academy of Sciences - PNAS</title><addtitle>Proc Natl Acad Sci U S A</addtitle><description>A systematic search has resulted in the synthesis of a class of cytokinin antimetabolites. The development and biological properties of the anticytokinins are discussed in terms of one member of the class, 3-methyl - 7 - (3 - methylbutylamino)pyrazolo[4,3 - d]- pyrimidine.</description><subject>Antimetabolites - pharmacology</subject><subject>Biochemistry</subject><subject>Biological Sciences: Biochemistry</subject><subject>Butylamines - pharmacology</subject><subject>Callus</subject><subject>Cytokinins</subject><subject>Kinins - antagonists & inhibitors</subject><subject>Nicotiana - drug effects</subject><subject>Plant Growth Regulators - antagonists & inhibitors</subject><subject>Plants</subject><subject>Plants, Toxic</subject><subject>Pyrazoles - pharmacology</subject><subject>Pyrimidines - pharmacology</subject><subject>Research grants</subject><issn>0027-8424</issn><issn>1091-6490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1LwzAYh4Moc07PgqD05qndm48mqeBhzE8Y6GH3kLbp7Oya0WTD_fe2bE538ZS8_J7nTfghdIkhwiDocFlrF3HZDhHhII9QH0OCQ84SOEZ9ACJCyQg7RWfOzQEgiSX0UC8mMpEJ7qNovPH2s6zL2t0FD2ZtKrtcmNoHtgh08G59dx_VXs9sXTp_jk4KXTlzsTsHaPr0OB2_hJO359fxaBJmjGMfCp3TJOaMyjjGkhMiRQoZ54IQFgsQLCaFyTHQVKRES46zVPPUUKEzynlOB-h-u3a5Shcmz9pPNLpSy6Zc6GajrC7VYVKXH2pm14rKhAnZ-sOtnzXWucYUexWD6npTXW-Ky27uemuN678v7vldUW1-s8s78Sc9WHD7L6CKVVV58-Vb8mpLzp23zS-KMQD9BmeWifE</recordid><startdate>19711001</startdate><enddate>19711001</enddate><creator>Hecht, Sidney M.</creator><creator>Bock, Robert M.</creator><creator>Schmitz, Ruth Y.</creator><creator>Skoog, Folke</creator><creator>Leonard, Nelson J.</creator><general>National Academy of Sciences of the United States of America</general><general>National Acad Sciences</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>19711001</creationdate><title>Cytokinins: Development of a Potent Antagonist</title><author>Hecht, Sidney M. ; Bock, Robert M. ; Schmitz, Ruth Y. ; Skoog, Folke ; Leonard, Nelson J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c461t-7ad3956438551862287b0c6672245707452fed103b7b2a861cba6be37ac366d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Antimetabolites - pharmacology</topic><topic>Biochemistry</topic><topic>Biological Sciences: Biochemistry</topic><topic>Butylamines - pharmacology</topic><topic>Callus</topic><topic>Cytokinins</topic><topic>Kinins - antagonists & inhibitors</topic><topic>Nicotiana - drug effects</topic><topic>Plant Growth Regulators - antagonists & inhibitors</topic><topic>Plants</topic><topic>Plants, Toxic</topic><topic>Pyrazoles - pharmacology</topic><topic>Pyrimidines - pharmacology</topic><topic>Research grants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hecht, Sidney M.</creatorcontrib><creatorcontrib>Bock, Robert M.</creatorcontrib><creatorcontrib>Schmitz, Ruth Y.</creatorcontrib><creatorcontrib>Skoog, Folke</creatorcontrib><creatorcontrib>Leonard, Nelson J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hecht, Sidney M.</au><au>Bock, Robert M.</au><au>Schmitz, Ruth Y.</au><au>Skoog, Folke</au><au>Leonard, Nelson J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cytokinins: Development of a Potent Antagonist</atitle><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle><addtitle>Proc Natl Acad Sci U S A</addtitle><date>1971-10-01</date><risdate>1971</risdate><volume>68</volume><issue>10</issue><spage>2608</spage><epage>2610</epage><pages>2608-2610</pages><issn>0027-8424</issn><eissn>1091-6490</eissn><abstract>A systematic search has resulted in the synthesis of a class of cytokinin antimetabolites. 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subjects | Antimetabolites - pharmacology Biochemistry Biological Sciences: Biochemistry Butylamines - pharmacology Callus Cytokinins Kinins - antagonists & inhibitors Nicotiana - drug effects Plant Growth Regulators - antagonists & inhibitors Plants Plants, Toxic Pyrazoles - pharmacology Pyrimidines - pharmacology Research grants |
title | Cytokinins: Development of a Potent Antagonist |
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