Hydrocarbon exposure and chronic glomerulonephritis

63 adult patients with advanced renal failure were interviewed to evaluate their exposure to chronically contacted or inhaled toxic substances. Grading of exposure revealed that patients with biopsy-proven primary proliferative glomerulonephritis and patients with a clinical presentation consistent...

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Veröffentlicht in:The Lancet (British edition) 1975-08, Vol.2 (7927), p.199
Hauptverfasser: Zimmerman, S W, Groehler, K, Beirne, G J
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container_title The Lancet (British edition)
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creator Zimmerman, S W
Groehler, K
Beirne, G J
description 63 adult patients with advanced renal failure were interviewed to evaluate their exposure to chronically contacted or inhaled toxic substances. Grading of exposure revealed that patients with biopsy-proven primary proliferative glomerulonephritis and patients with a clinical presentation consistent with glomerulonephritis had significantly greater exposure than patients with a variety of other renal diseases. Patients with proliferative or suspected glomerulonephritis also had significantly more exposure than age and sex matched controls without renal disease. Hydrocarbon solvents were the most frequent agents of exposure. Further studies to define a possible pathogenic relationship between hydrocarbon exposure and glomerulonephritis are warranted.
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identifier ISSN: 0140-6736
ispartof The Lancet (British edition), 1975-08, Vol.2 (7927), p.199
issn 0140-6736
language eng
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source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects Adult
Aged
Chronic Disease
Environmental Exposure
Female
Glomerulonephritis - chemically induced
Glomerulonephritis - pathology
Humans
Hydrocarbons - adverse effects
Kidney Diseases - pathology
Male
Middle Aged
title Hydrocarbon exposure and chronic glomerulonephritis
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