Histopathology of Tumors of Canine Alimentary Tract Produced by N-Methyl-N'-nitro-N-nitrosoguanidine, With Particular Reference to Gastric Carcinomas

Four 90-day-old dogs were given 167 µg/ml solution of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) orally for 1 month and 83 µg/ml of solution for the following 14 months. All dogs developed adenocarcinomas, often multiple, of the stomach, the diagnosis of which was based entirely on the histolo...

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Veröffentlicht in:JNCI : Journal of the National Cancer Institute 1971-11, Vol.47 (5), p.1053-1070
Hauptverfasser: Shimosato, Yukio, Tanaka, Noritake, Kogure, Kikuko, Fujimura, Shinji, Kawachi, Takashi, Sugimura, Takashi
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Sprache:eng
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