LONG-TERM EXPERIMENT OF MAXIMAL NON-CARCINOGENIC DOSE OF DIMETHYLNITROSAMINE FOR CARCINOGENESIS IN RATS

Studies were made on the maximal non-carcinogenic dose of dimethylnitrosamine (DMN) in rats. Groups of Wistar strain rats of both sexes, 6 weeks old, were given standard diet without DMN (group 1), or containing 0.1ppm DMN (group 2), 1.0ppm DMN (group 3), or 10ppm DMN (group 4) for 96 weeks and then...

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Veröffentlicht in:	GANN Japanese Journal of Cancer Research 1979/08/31, Vol.70(4), pp.549-558
Hauptverfasser:	ARAI, Masayuki, AOKI, Yoshinari, NAKANISHI, Keisuke, MIYATA, Yukitada, MORI, Tomizo, ITO, Nobuyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Weight - drug effects Carcinogenesis Dimethylnitrosamine Dimethylnitrosamine - administration & dosage Dimethylnitrosamine - toxicity Dose-Response Relationship, Drug Female Liver Neoplasms, Experimental - chemically induced Male Maximum Allowable Concentration Maximum non-carcinogenic dose Rats Wistar rat
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