Ultrastructure of doxorubicin (adriamycin)-induced skin ulcers in rats

Skin necrosis was produced in 24 male Fischer 344 rats by intradermal injection of 0.5 ml of doxorubicin (Adriamycin) at a concentration of 2 mg/ml. The resulting wounds healed slowly over 6 to 7 weeks with the reduced contraction rate paralleling the prolonged morbidity of doxorubicin ulcers in hum...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1979-09, Vol.39 (9), p.3689
Hauptverfasser:	Rudolph, R, Woodward, M, Hurn, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Doxorubicin - adverse effects Endoplasmic Reticulum - ultrastructure Male Mitochondrial Swelling Myofibrils - ultrastructure Necrosis - pathology Rats Rats, Inbred F344 Skin Ulcer - chemically induced Skin Ulcer - pathology Time Factors Wound Healing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!