Renal Carcinoma with Increased Erythropoietin Production and Secondary Polycythemia
A report on a patient with renal carcinoma with increased erythropoietin production and secondary polycythemia is given. After nephrectomy, the hemoglobin and hematocrit values decreased to normal levels. For some months after the operation, the patient had no symptoms, but the hemoglobin and hemato...
Gespeichert in:
| Veröffentlicht in: | Scandinavian journal of urology and nephrology 1973, Vol.7 (2-3), p.178-180 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 180 |
|---|---|
| container_issue | 2-3 |
| container_start_page | 178 |
| container_title | Scandinavian journal of urology and nephrology |
| container_volume | 7 |
| creator | Kvarstein, Bernt Lindemann, Rolf Mathisen, Willy |
| description | A report on a patient with renal carcinoma with increased erythropoietin production and secondary polycythemia is given. After nephrectomy, the hemoglobin and hematocrit values decreased to normal levels. For some months after the operation, the patient had no symptoms, but the hemoglobin and hematocrit values were increasing, indicating a recurrence of the tumor. It was also found that the serum erythropoietin level had increased considerably. On re-operation, a recidivating tumor was found. test material was injected on two consecutive days, each day either 0.5 ml plasma or 0.5 ml urine extract. The concentrated urine was dissolved in 5 ml 0.154 M Nacl prior to injection. Five mice were used in each assay group. The percentage incorporation of 59Fe in the erythrocytes was used as a parameter and was then correlated to a dose-response curve of International Standard B Erythropoietin (WHO International Laboratories for Biological Standards, Mill Hill, London, England). |
| doi_str_mv | 10.3109/00365597309133698 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_4759782</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>82117714</sourcerecordid><originalsourceid>FETCH-LOGICAL-c401t-b1f7363c75446f9dca59f0dd098ab9e00b9c7e7b9c2410720ad50fbd55cfcf43</originalsourceid><addsrcrecordid>eNp9kUtLw0AUhQdRan38ABdCVu6id5JMpoNupNQHFBR1H27mQackM3UmofTfm9IiiOjm3sU55-NyLiEXFK5zCuIGIC8ZEzwHQfO8FJMDMqYlo2kGJTsk462eDgZxTE5iXAJAVtJyREYFH1KTbEze37TDJplikNb5FpO17RbJs5NBY9QqmYVNtwh-5a3urEteg1e97Kx3CTqVvGvpncKwSV59s5GDVbcWz8iRwSbq8_0-JR8Ps4_pUzp_eXye3s9TWQDt0poanpe55KwoSiOURCYMKAVigrXQALWQXPNhZgUFngEqBqZWjEkjTZGfkqsddhX8Z69jV7U2St006LTvYzXJKOWcbo10Z5TBxxi0qVbBtsPVFYVq22P1q8chc7mH93Wr1XdiX9yg3-1064wPLa59aFTV4abxwQR00sYt-m_87Y_4QmPTLSQGXS19H4aXxH-O-wIhwZRa</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>82117714</pqid></control><display><type>article</type><title>Renal Carcinoma with Increased Erythropoietin Production and Secondary Polycythemia</title><source>MEDLINE</source><source>Taylor & Francis:Master (3349 titles)</source><source>Taylor & Francis Medical Library - CRKN</source><creator>Kvarstein, Bernt ; Lindemann, Rolf ; Mathisen, Willy</creator><creatorcontrib>Kvarstein, Bernt ; Lindemann, Rolf ; Mathisen, Willy</creatorcontrib><description>A report on a patient with renal carcinoma with increased erythropoietin production and secondary polycythemia is given. After nephrectomy, the hemoglobin and hematocrit values decreased to normal levels. For some months after the operation, the patient had no symptoms, but the hemoglobin and hematocrit values were increasing, indicating a recurrence of the tumor. It was also found that the serum erythropoietin level had increased considerably. On re-operation, a recidivating tumor was found. test material was injected on two consecutive days, each day either 0.5 ml plasma or 0.5 ml urine extract. The concentrated urine was dissolved in 5 ml 0.154 M Nacl prior to injection. Five mice were used in each assay group. The percentage incorporation of 59Fe in the erythrocytes was used as a parameter and was then correlated to a dose-response curve of International Standard B Erythropoietin (WHO International Laboratories for Biological Standards, Mill Hill, London, England).</description><identifier>ISSN: 0036-5599</identifier><identifier>EISSN: 1651-2065</identifier><identifier>DOI: 10.3109/00365597309133698</identifier><identifier>PMID: 4759782</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adenocarcinoma - blood ; Adenocarcinoma - complications ; Adenocarcinoma - therapy ; Erythrocytes - metabolism ; Erythropoietin - blood ; Erythropoietin - metabolism ; Erythropoietin - urine ; Hematocrit ; Hemoglobins - metabolism ; Humans ; Iron Radioisotopes ; Kidney Neoplasms - blood ; Kidney Neoplasms - complications ; Kidney Neoplasms - therapy ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Nephrectomy ; Polycythemia - etiology ; Time Factors</subject><ispartof>Scandinavian journal of urology and nephrology, 1973, Vol.7 (2-3), p.178-180</ispartof><rights>1973 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1973</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c401t-b1f7363c75446f9dca59f0dd098ab9e00b9c7e7b9c2410720ad50fbd55cfcf43</citedby><cites>FETCH-LOGICAL-c401t-b1f7363c75446f9dca59f0dd098ab9e00b9c7e7b9c2410720ad50fbd55cfcf43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/00365597309133698$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/00365597309133698$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>315,781,785,4025,27925,27926,27927,59649,59755,60438,60544,61223,61258,61404,61439</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4759782$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kvarstein, Bernt</creatorcontrib><creatorcontrib>Lindemann, Rolf</creatorcontrib><creatorcontrib>Mathisen, Willy</creatorcontrib><title>Renal Carcinoma with Increased Erythropoietin Production and Secondary Polycythemia</title><title>Scandinavian journal of urology and nephrology</title><addtitle>Scand J Urol Nephrol</addtitle><description>A report on a patient with renal carcinoma with increased erythropoietin production and secondary polycythemia is given. After nephrectomy, the hemoglobin and hematocrit values decreased to normal levels. For some months after the operation, the patient had no symptoms, but the hemoglobin and hematocrit values were increasing, indicating a recurrence of the tumor. It was also found that the serum erythropoietin level had increased considerably. On re-operation, a recidivating tumor was found. test material was injected on two consecutive days, each day either 0.5 ml plasma or 0.5 ml urine extract. The concentrated urine was dissolved in 5 ml 0.154 M Nacl prior to injection. Five mice were used in each assay group. The percentage incorporation of 59Fe in the erythrocytes was used as a parameter and was then correlated to a dose-response curve of International Standard B Erythropoietin (WHO International Laboratories for Biological Standards, Mill Hill, London, England).</description><subject>Adenocarcinoma - blood</subject><subject>Adenocarcinoma - complications</subject><subject>Adenocarcinoma - therapy</subject><subject>Erythrocytes - metabolism</subject><subject>Erythropoietin - blood</subject><subject>Erythropoietin - metabolism</subject><subject>Erythropoietin - urine</subject><subject>Hematocrit</subject><subject>Hemoglobins - metabolism</subject><subject>Humans</subject><subject>Iron Radioisotopes</subject><subject>Kidney Neoplasms - blood</subject><subject>Kidney Neoplasms - complications</subject><subject>Kidney Neoplasms - therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neoplasm Recurrence, Local</subject><subject>Nephrectomy</subject><subject>Polycythemia - etiology</subject><subject>Time Factors</subject><issn>0036-5599</issn><issn>1651-2065</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUtLw0AUhQdRan38ABdCVu6id5JMpoNupNQHFBR1H27mQackM3UmofTfm9IiiOjm3sU55-NyLiEXFK5zCuIGIC8ZEzwHQfO8FJMDMqYlo2kGJTsk462eDgZxTE5iXAJAVtJyREYFH1KTbEze37TDJplikNb5FpO17RbJs5NBY9QqmYVNtwh-5a3urEteg1e97Kx3CTqVvGvpncKwSV59s5GDVbcWz8iRwSbq8_0-JR8Ps4_pUzp_eXye3s9TWQDt0poanpe55KwoSiOURCYMKAVigrXQALWQXPNhZgUFngEqBqZWjEkjTZGfkqsddhX8Z69jV7U2St006LTvYzXJKOWcbo10Z5TBxxi0qVbBtsPVFYVq22P1q8chc7mH93Wr1XdiX9yg3-1064wPLa59aFTV4abxwQR00sYt-m_87Y_4QmPTLSQGXS19H4aXxH-O-wIhwZRa</recordid><startdate>1973</startdate><enddate>1973</enddate><creator>Kvarstein, Bernt</creator><creator>Lindemann, Rolf</creator><creator>Mathisen, Willy</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1973</creationdate><title>Renal Carcinoma with Increased Erythropoietin Production and Secondary Polycythemia</title><author>Kvarstein, Bernt ; Lindemann, Rolf ; Mathisen, Willy</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c401t-b1f7363c75446f9dca59f0dd098ab9e00b9c7e7b9c2410720ad50fbd55cfcf43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Adenocarcinoma - blood</topic><topic>Adenocarcinoma - complications</topic><topic>Adenocarcinoma - therapy</topic><topic>Erythrocytes - metabolism</topic><topic>Erythropoietin - blood</topic><topic>Erythropoietin - metabolism</topic><topic>Erythropoietin - urine</topic><topic>Hematocrit</topic><topic>Hemoglobins - metabolism</topic><topic>Humans</topic><topic>Iron Radioisotopes</topic><topic>Kidney Neoplasms - blood</topic><topic>Kidney Neoplasms - complications</topic><topic>Kidney Neoplasms - therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neoplasm Recurrence, Local</topic><topic>Nephrectomy</topic><topic>Polycythemia - etiology</topic><topic>Time Factors</topic><toplevel>online_resources</toplevel><creatorcontrib>Kvarstein, Bernt</creatorcontrib><creatorcontrib>Lindemann, Rolf</creatorcontrib><creatorcontrib>Mathisen, Willy</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of urology and nephrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kvarstein, Bernt</au><au>Lindemann, Rolf</au><au>Mathisen, Willy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Renal Carcinoma with Increased Erythropoietin Production and Secondary Polycythemia</atitle><jtitle>Scandinavian journal of urology and nephrology</jtitle><addtitle>Scand J Urol Nephrol</addtitle><date>1973</date><risdate>1973</risdate><volume>7</volume><issue>2-3</issue><spage>178</spage><epage>180</epage><pages>178-180</pages><issn>0036-5599</issn><eissn>1651-2065</eissn><abstract>A report on a patient with renal carcinoma with increased erythropoietin production and secondary polycythemia is given. After nephrectomy, the hemoglobin and hematocrit values decreased to normal levels. For some months after the operation, the patient had no symptoms, but the hemoglobin and hematocrit values were increasing, indicating a recurrence of the tumor. It was also found that the serum erythropoietin level had increased considerably. On re-operation, a recidivating tumor was found. test material was injected on two consecutive days, each day either 0.5 ml plasma or 0.5 ml urine extract. The concentrated urine was dissolved in 5 ml 0.154 M Nacl prior to injection. Five mice were used in each assay group. The percentage incorporation of 59Fe in the erythrocytes was used as a parameter and was then correlated to a dose-response curve of International Standard B Erythropoietin (WHO International Laboratories for Biological Standards, Mill Hill, London, England).</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>4759782</pmid><doi>10.3109/00365597309133698</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-5599 |
| ispartof | Scandinavian journal of urology and nephrology, 1973, Vol.7 (2-3), p.178-180 |
| issn | 0036-5599 1651-2065 |
| language | eng |
| recordid | cdi_pubmed_primary_4759782 |
| source | MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN |
| subjects | Adenocarcinoma - blood Adenocarcinoma - complications Adenocarcinoma - therapy Erythrocytes - metabolism Erythropoietin - blood Erythropoietin - metabolism Erythropoietin - urine Hematocrit Hemoglobins - metabolism Humans Iron Radioisotopes Kidney Neoplasms - blood Kidney Neoplasms - complications Kidney Neoplasms - therapy Male Middle Aged Neoplasm Recurrence, Local Nephrectomy Polycythemia - etiology Time Factors |
| title | Renal Carcinoma with Increased Erythropoietin Production and Secondary Polycythemia |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T06%3A08%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Renal%20Carcinoma%20with%20Increased%20Erythropoietin%20Production%20and%20Secondary%20Polycythemia&rft.jtitle=Scandinavian%20journal%20of%20urology%20and%20nephrology&rft.au=Kvarstein,%20Bernt&rft.date=1973&rft.volume=7&rft.issue=2-3&rft.spage=178&rft.epage=180&rft.pages=178-180&rft.issn=0036-5599&rft.eissn=1651-2065&rft_id=info:doi/10.3109/00365597309133698&rft_dat=%3Cproquest_pubme%3E82117714%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=82117714&rft_id=info:pmid/4759782&rfr_iscdi=true |