The Relationship between Acid, Pepsin, and Electrolytes in Gastric Juice before and after Subcutaneous Injection of Histamine in Man
The gastric secretion of acid (TA), pepsin (CPU), sodium (Na), potassium (K), and magnesium (Mg), was studied in 14 patients before and after subcutaneous injection of 0.04 mg histamine diphosphate. The concentrations ([]) and outputs (Q) of TA, CPU, and K increased significantly after stimulation w...
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| Veröffentlicht in: | Scandinavian journal of gastroenterology 1972, Vol.7 (1), p.17-21 |
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| creator | Semb, L. S. |
| description | The gastric secretion of acid (TA), pepsin (CPU), sodium (Na), potassium (K), and magnesium (Mg), was studied in 14 patients before and after subcutaneous injection of 0.04 mg histamine diphosphate. The concentrations ([]) and outputs (Q) of TA, CPU, and K increased significantly after stimulation with histamine, while the [Mg] and [Na] decreased. The QNa was unchanged by histamine-stimulation, whereas QMg showed a significant increase in the first 20-minute period after histamine-stimulation. A correlation analysis between the parameters showed positive correlations between TA and CPU, TA and K, and a negative correlation between [TA] and [NA] or [Mg], There was a significant positive correlation between Na and Mg, but no significant correlation between CPU and Mg or Na. It is suggested that Mg stems from a different non-parietal cell secretion than pepsin, but that it probably has the same origin as Na. |
| doi_str_mv | 10.3109/00365527209180732 |
| format | Article |
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S.</creator><creatorcontrib>Semb, L. S.</creatorcontrib><description>The gastric secretion of acid (TA), pepsin (CPU), sodium (Na), potassium (K), and magnesium (Mg), was studied in 14 patients before and after subcutaneous injection of 0.04 mg histamine diphosphate. The concentrations ([]) and outputs (Q) of TA, CPU, and K increased significantly after stimulation with histamine, while the [Mg] and [Na] decreased. The QNa was unchanged by histamine-stimulation, whereas QMg showed a significant increase in the first 20-minute period after histamine-stimulation. A correlation analysis between the parameters showed positive correlations between TA and CPU, TA and K, and a negative correlation between [TA] and [NA] or [Mg], There was a significant positive correlation between Na and Mg, but no significant correlation between CPU and Mg or Na. 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S.</creatorcontrib><title>The Relationship between Acid, Pepsin, and Electrolytes in Gastric Juice before and after Subcutaneous Injection of Histamine in Man</title><title>Scandinavian journal of gastroenterology</title><addtitle>Scand J Gastroenterol</addtitle><description>The gastric secretion of acid (TA), pepsin (CPU), sodium (Na), potassium (K), and magnesium (Mg), was studied in 14 patients before and after subcutaneous injection of 0.04 mg histamine diphosphate. The concentrations ([]) and outputs (Q) of TA, CPU, and K increased significantly after stimulation with histamine, while the [Mg] and [Na] decreased. The QNa was unchanged by histamine-stimulation, whereas QMg showed a significant increase in the first 20-minute period after histamine-stimulation. A correlation analysis between the parameters showed positive correlations between TA and CPU, TA and K, and a negative correlation between [TA] and [NA] or [Mg], There was a significant positive correlation between Na and Mg, but no significant correlation between CPU and Mg or Na. It is suggested that Mg stems from a different non-parietal cell secretion than pepsin, but that it probably has the same origin as Na.</description><subject>Adult</subject><subject>Depression, Chemical</subject><subject>Electrolytes</subject><subject>Female</subject><subject>gastric juice</subject><subject>Gastric Juice - analysis</subject><subject>Gastric Juice - metabolism</subject><subject>Histamine - pharmacology</subject><subject>Humans</subject><subject>hydrochloric acid</subject><subject>magnesium</subject><subject>Magnesium - metabolism</subject><subject>Male</subject><subject>Middle Aged</subject><subject>pepsin</subject><subject>Pepsin A - metabolism</subject><subject>potassium</subject><subject>Potassium - metabolism</subject><subject>Secretory Rate - drug effects</subject><subject>sodium</subject><subject>Sodium - metabolism</subject><subject>Stimulation, Chemical</subject><issn>0036-5521</issn><issn>1502-7708</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM9rFDEYhoModa3-AR6EnDx1NJlMJjPopZTaViqK1vOQH1_YLJlkTTKUvfuHN-sugoiecnjf58nHi9BLSt4wSsa3hLCe81a0ZKQDEax9hFaUk7YRggyP0WqfN7VAn6JnOW8IIVx04wk66TinPelX6OfdGvBX8LK4GPLabbGCcg8Q8Ll25gx_gW124QzLYPClB11S9LsCGbuAr2QuyWn8cXEaKmdjgl9FaQsk_G1ReikyQFwyvgmbCtc_cLT42uUiZxdgb_kkw3P0xEqf4cXxPUXfP1zeXVw3t5-vbi7ObxvNaF8aJbkYmBJ6GLkQFrg2bQecsVYbOkjat0QB6RQHyzjIYVDGEKMtU9D1HFp2il4fvNsUfyyQyzS7rMH7w5HTQNk4UtHVIj0UdYo5J7DTNrlZpt1EybRffvpr-cq8OsoXNYP5TRynrvn7Q-5CHWqW9zF5MxW58zHZJIN2ea_-t_7dH_gapC9rLRNMm7ikUHf7z3EPZTKk9A</recordid><startdate>1972</startdate><enddate>1972</enddate><creator>Semb, L. S.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1972</creationdate><title>The Relationship between Acid, Pepsin, and Electrolytes in Gastric Juice before and after Subcutaneous Injection of Histamine in Man</title><author>Semb, L. S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c316t-ba5783b7c89577fe5cd24e5332cd18a1620be04b5ef35ea88bdd0dcf3be465e23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Adult</topic><topic>Depression, Chemical</topic><topic>Electrolytes</topic><topic>Female</topic><topic>gastric juice</topic><topic>Gastric Juice - analysis</topic><topic>Gastric Juice - metabolism</topic><topic>Histamine - pharmacology</topic><topic>Humans</topic><topic>hydrochloric acid</topic><topic>magnesium</topic><topic>Magnesium - metabolism</topic><topic>Male</topic><topic>Middle Aged</topic><topic>pepsin</topic><topic>Pepsin A - metabolism</topic><topic>potassium</topic><topic>Potassium - metabolism</topic><topic>Secretory Rate - drug effects</topic><topic>sodium</topic><topic>Sodium - metabolism</topic><topic>Stimulation, Chemical</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Semb, L. S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Semb, L. S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Relationship between Acid, Pepsin, and Electrolytes in Gastric Juice before and after Subcutaneous Injection of Histamine in Man</atitle><jtitle>Scandinavian journal of gastroenterology</jtitle><addtitle>Scand J Gastroenterol</addtitle><date>1972</date><risdate>1972</risdate><volume>7</volume><issue>1</issue><spage>17</spage><epage>21</epage><pages>17-21</pages><issn>0036-5521</issn><eissn>1502-7708</eissn><abstract>The gastric secretion of acid (TA), pepsin (CPU), sodium (Na), potassium (K), and magnesium (Mg), was studied in 14 patients before and after subcutaneous injection of 0.04 mg histamine diphosphate. The concentrations ([]) and outputs (Q) of TA, CPU, and K increased significantly after stimulation with histamine, while the [Mg] and [Na] decreased. The QNa was unchanged by histamine-stimulation, whereas QMg showed a significant increase in the first 20-minute period after histamine-stimulation. A correlation analysis between the parameters showed positive correlations between TA and CPU, TA and K, and a negative correlation between [TA] and [NA] or [Mg], There was a significant positive correlation between Na and Mg, but no significant correlation between CPU and Mg or Na. It is suggested that Mg stems from a different non-parietal cell secretion than pepsin, but that it probably has the same origin as Na.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>4551606</pmid><doi>10.3109/00365527209180732</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-5521 |
| ispartof | Scandinavian journal of gastroenterology, 1972, Vol.7 (1), p.17-21 |
| issn | 0036-5521 1502-7708 |
| language | eng |
| recordid | cdi_pubmed_primary_4551606 |
| source | Taylor & Francis; MEDLINE; Taylor & Francis Medical Library - CRKN |
| subjects | Adult Depression, Chemical Electrolytes Female gastric juice Gastric Juice - analysis Gastric Juice - metabolism Histamine - pharmacology Humans hydrochloric acid magnesium Magnesium - metabolism Male Middle Aged pepsin Pepsin A - metabolism potassium Potassium - metabolism Secretory Rate - drug effects sodium Sodium - metabolism Stimulation, Chemical |
| title | The Relationship between Acid, Pepsin, and Electrolytes in Gastric Juice before and after Subcutaneous Injection of Histamine in Man |
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