Effect of 7,12-dimethylbenz(a)anthracene on the binding of aminoacyl transfer RNA in rat liver

Homogenates of the liver of female rats obtained 2 or 7 days or 3 months after the i.v. injection of 7,12-dimethylbenz(a)anthracene were used to prepare ribosomes and postmicrosomal supernatant fractions and to prepare 0.5 M KCl salt wash fractions of the 40 S ribosomal subunits. The activity of the...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1977-11, Vol.37 (11), p.4220
Hauptverfasser:	Chan, Y P, Sendecki, W, Nicholls, D M
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene - pharmacology Animals Benz(a)Anthracenes - pharmacology DDT - pharmacology Female In Vitro Techniques Liver - drug effects Liver - metabolism Mammary Neoplasms, Experimental - chemically induced Mammary Neoplasms, Experimental - metabolism Methionine - metabolism Peptide Biosynthesis Peptide Elongation Factors Peptide Initiation Factors - isolation & purification Phenylalanine - metabolism Rats Ribosomes - metabolism RNA, Transfer, Amino Acyl - metabolism
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