The enzymatic degradation of DDT. 3. Metabolism of DDT
DDT orally given to rats is converted into DDD by reductive dechlorination in the liver within 30 min. 6 h after a single application of 10 mg DDT per rat a quantity of 60 mg DDD/kg was indicated in the liver. DDT is stored in the adrenal glands; in the other organs an equilibrium comes up obviously...
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Veröffentlicht in: | Die Nahrung 1985, Vol.29 (4), p.405 |
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container_title | Die Nahrung |
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creator | Kujawa, M Macholz, R M Plass, R Knoll, R Engst, R |
description | DDT orally given to rats is converted into DDD by reductive dechlorination in the liver within 30 min. 6 h after a single application of 10 mg DDT per rat a quantity of 60 mg DDD/kg was indicated in the liver. DDT is stored in the adrenal glands; in the other organs an equilibrium comes up obviously, even with further application. The quantitative ratios are reported. Information on the experimental details of DDT determination and--anticipatory to the following publications--on the analysis of the most relevant metabolites is given. |
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Information on the experimental details of DDT determination and--anticipatory to the following publications--on the analysis of the most relevant metabolites is given.</description><identifier>ISSN: 0027-769X</identifier><identifier>PMID: 4022107</identifier><language>ger</language><publisher>Germany</publisher><subject>Animals ; Biodegradation, Environmental ; Biotransformation ; Chromatography, Gas ; Chromatography, Thin Layer ; DDT - metabolism ; DDT - urine ; Dichlorodiphenyldichloroethane - metabolism ; Feces - analysis ; Kinetics ; Male ; Rats ; Rats, Inbred Strains ; Tissue Distribution</subject><ispartof>Die Nahrung, 1985, Vol.29 (4), p.405</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,4012</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4022107$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kujawa, M</creatorcontrib><creatorcontrib>Macholz, R M</creatorcontrib><creatorcontrib>Plass, R</creatorcontrib><creatorcontrib>Knoll, R</creatorcontrib><creatorcontrib>Engst, R</creatorcontrib><title>The enzymatic degradation of DDT. 3. Metabolism of DDT</title><title>Die Nahrung</title><addtitle>Nahrung</addtitle><description>DDT orally given to rats is converted into DDD by reductive dechlorination in the liver within 30 min. 6 h after a single application of 10 mg DDT per rat a quantity of 60 mg DDD/kg was indicated in the liver. DDT is stored in the adrenal glands; in the other organs an equilibrium comes up obviously, even with further application. The quantitative ratios are reported. Information on the experimental details of DDT determination and--anticipatory to the following publications--on the analysis of the most relevant metabolites is given.</description><subject>Animals</subject><subject>Biodegradation, Environmental</subject><subject>Biotransformation</subject><subject>Chromatography, Gas</subject><subject>Chromatography, Thin Layer</subject><subject>DDT - metabolism</subject><subject>DDT - urine</subject><subject>Dichlorodiphenyldichloroethane - metabolism</subject><subject>Feces - analysis</subject><subject>Kinetics</subject><subject>Male</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Tissue Distribution</subject><issn>0027-769X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotjstqwzAQRbVoSdK0nxDQDziMNLLkWZakj0BKNy50FyRr1LrEsbHdRfL1KdSreziLw70RCwDtMmfpcy7uhuEHACw5nImZAa0VuIWw5TdLPl3OjR_rSkb-6n38w_Yk2yS323ItcS3fePShPdZDM9l7cZv8ceCHaZfi4_mp3Lxm-_eX3eZxn3UKizFLkdA49EyqUMpUNhSWbTSQU0WkjcEcXCqCwqQDeqcILSK7PDFF4xMuxeq_2_2GhuOh6-vG9-fD9B-vo5c9mA</recordid><startdate>1985</startdate><enddate>1985</enddate><creator>Kujawa, M</creator><creator>Macholz, R M</creator><creator>Plass, R</creator><creator>Knoll, R</creator><creator>Engst, R</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>1985</creationdate><title>The enzymatic degradation of DDT. 3. Metabolism of DDT</title><author>Kujawa, M ; Macholz, R M ; Plass, R ; Knoll, R ; Engst, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p138t-fd93473ae918114c6b86e6d4059c992443507f8b13f2b3a7193633e75fe9d4af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>ger</language><creationdate>1985</creationdate><topic>Animals</topic><topic>Biodegradation, Environmental</topic><topic>Biotransformation</topic><topic>Chromatography, Gas</topic><topic>Chromatography, Thin Layer</topic><topic>DDT - metabolism</topic><topic>DDT - urine</topic><topic>Dichlorodiphenyldichloroethane - metabolism</topic><topic>Feces - analysis</topic><topic>Kinetics</topic><topic>Male</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Tissue Distribution</topic><toplevel>online_resources</toplevel><creatorcontrib>Kujawa, M</creatorcontrib><creatorcontrib>Macholz, R M</creatorcontrib><creatorcontrib>Plass, R</creatorcontrib><creatorcontrib>Knoll, R</creatorcontrib><creatorcontrib>Engst, R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Die Nahrung</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kujawa, M</au><au>Macholz, R M</au><au>Plass, R</au><au>Knoll, R</au><au>Engst, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The enzymatic degradation of DDT. 3. 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source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
subjects | Animals Biodegradation, Environmental Biotransformation Chromatography, Gas Chromatography, Thin Layer DDT - metabolism DDT - urine Dichlorodiphenyldichloroethane - metabolism Feces - analysis Kinetics Male Rats Rats, Inbred Strains Tissue Distribution |
title | The enzymatic degradation of DDT. 3. Metabolism of DDT |
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