Effect of 3-methylcholanthrene on the development of aortic lesions in mice

The effect of a carcinogen, 3-methylcholanthrene (3-MC), on the formation and growth of atherosclerotic lesions in mice was examined. Increasing doses of 3-MC from 15 to 1500 micrograms/kg increased the number and size of lipid-staining lesions in the aorta of AKXL-38a mice that were fed an atheroge...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 1985-08, Vol.45 (8), p.3850-3855
Hauptverfasser: PAIGEN, B, HAVENS, M. B, MORROW, A
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Sprache:eng
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