Comparison of X-Ray Attenuation Performance, Antimicrobial Properties, and Cytotoxicity of Silicone-Based Matrices Containing Bi 2 O 3 , PbO, or Bi 2 O 3 /PbO Nanoparticles
Application of the nanomaterials to preparing X-ray shields and successfully treating multiresistant microorganisms has attracted great attention in modern life. This study aimed to prepare flexible silicone-based matrices containing Bi O , PbO, or Bi O /PbO nanoparticles and select a cost-effective...
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Veröffentlicht in: | Journal of biomedical physics and engineering 2024-12, Vol.14 (6), p.533 |
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creator | Divband, Baharak Haleem Al-Qaim, Zahraa Hussein, Falah H Khezerloo, Davood Gharehaghaji, Nahideh |
description | Application of the nanomaterials to preparing X-ray shields and successfully treating multiresistant microorganisms has attracted great attention in modern life.
This study aimed to prepare flexible silicone-based matrices containing Bi
O
, PbO, or Bi
O
/PbO nanoparticles and select a cost-effective, cytocompatible, and antibacterial/antifungal X-ray shield in clinical radiography.
In this experimental study, we prepared the nanoparticles by the modified biosynthesis method and fabricated the X-ray shields containing 20 wt% of the nanoparticles. The X-ray attenuation percentage and Half Value Layer (HVL) of the shields were investigated for the photon energies in the range of 40-100 kVp in clinical radiography. The antibacterial/antifungal activities of the shields were evaluated using a colony count method for the gram-negative (
), and gram-positive (
) bacteria, and Candida albicans fungus. The shield toxicity was investigated on A549 cells.
The highest X-ray attenuation percentage and the lowest HVL were obtained using the shield containing Bi
O
nanoparticles. Although all shields displayed antimicrobial activity, the shield containing Bi
O
/PbO nanoparticles showed the most effective reduction in the colony counts. Both X-ray shields containing nano Bi
O
and Bi
O
/PbO demonstrated high cytocompatibility on A549 cells at a concentration as high as 500 µg/ml. The shield with PbO nanoparticles was also cytocompatible at a concentration of 50 µg/ml.
The best X-ray attenuation performance is attributed to the silicone-based matrix with nano Bi
O
; however, the flexible shield with Bi
O
/PbO nanoparticles can be cost-effective and cytocompatible with the best antibacterial/antifungal properties. |
doi_str_mv | 10.31661/jbpe.v0i0.2403-1736 |
format | Article |
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This study aimed to prepare flexible silicone-based matrices containing Bi
O
, PbO, or Bi
O
/PbO nanoparticles and select a cost-effective, cytocompatible, and antibacterial/antifungal X-ray shield in clinical radiography.
In this experimental study, we prepared the nanoparticles by the modified biosynthesis method and fabricated the X-ray shields containing 20 wt% of the nanoparticles. The X-ray attenuation percentage and Half Value Layer (HVL) of the shields were investigated for the photon energies in the range of 40-100 kVp in clinical radiography. The antibacterial/antifungal activities of the shields were evaluated using a colony count method for the gram-negative (
), and gram-positive (
) bacteria, and Candida albicans fungus. The shield toxicity was investigated on A549 cells.
The highest X-ray attenuation percentage and the lowest HVL were obtained using the shield containing Bi
O
nanoparticles. Although all shields displayed antimicrobial activity, the shield containing Bi
O
/PbO nanoparticles showed the most effective reduction in the colony counts. Both X-ray shields containing nano Bi
O
and Bi
O
/PbO demonstrated high cytocompatibility on A549 cells at a concentration as high as 500 µg/ml. The shield with PbO nanoparticles was also cytocompatible at a concentration of 50 µg/ml.
The best X-ray attenuation performance is attributed to the silicone-based matrix with nano Bi
O
; however, the flexible shield with Bi
O
/PbO nanoparticles can be cost-effective and cytocompatible with the best antibacterial/antifungal properties.</description><identifier>ISSN: 2251-7200</identifier><identifier>EISSN: 2251-7200</identifier><identifier>DOI: 10.31661/jbpe.v0i0.2403-1736</identifier><identifier>PMID: 39726880</identifier><language>eng</language><publisher>Iran</publisher><ispartof>Journal of biomedical physics and engineering, 2024-12, Vol.14 (6), p.533</ispartof><rights>Copyright: © Journal of Biomedical Physics and Engineering.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,860,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39726880$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Divband, Baharak</creatorcontrib><creatorcontrib>Haleem Al-Qaim, Zahraa</creatorcontrib><creatorcontrib>Hussein, Falah H</creatorcontrib><creatorcontrib>Khezerloo, Davood</creatorcontrib><creatorcontrib>Gharehaghaji, Nahideh</creatorcontrib><title>Comparison of X-Ray Attenuation Performance, Antimicrobial Properties, and Cytotoxicity of Silicone-Based Matrices Containing Bi 2 O 3 , PbO, or Bi 2 O 3 /PbO Nanoparticles</title><title>Journal of biomedical physics and engineering</title><addtitle>J Biomed Phys Eng</addtitle><description>Application of the nanomaterials to preparing X-ray shields and successfully treating multiresistant microorganisms has attracted great attention in modern life.
This study aimed to prepare flexible silicone-based matrices containing Bi
O
, PbO, or Bi
O
/PbO nanoparticles and select a cost-effective, cytocompatible, and antibacterial/antifungal X-ray shield in clinical radiography.
In this experimental study, we prepared the nanoparticles by the modified biosynthesis method and fabricated the X-ray shields containing 20 wt% of the nanoparticles. The X-ray attenuation percentage and Half Value Layer (HVL) of the shields were investigated for the photon energies in the range of 40-100 kVp in clinical radiography. The antibacterial/antifungal activities of the shields were evaluated using a colony count method for the gram-negative (
), and gram-positive (
) bacteria, and Candida albicans fungus. The shield toxicity was investigated on A549 cells.
The highest X-ray attenuation percentage and the lowest HVL were obtained using the shield containing Bi
O
nanoparticles. Although all shields displayed antimicrobial activity, the shield containing Bi
O
/PbO nanoparticles showed the most effective reduction in the colony counts. Both X-ray shields containing nano Bi
O
and Bi
O
/PbO demonstrated high cytocompatibility on A549 cells at a concentration as high as 500 µg/ml. The shield with PbO nanoparticles was also cytocompatible at a concentration of 50 µg/ml.
The best X-ray attenuation performance is attributed to the silicone-based matrix with nano Bi
O
; however, the flexible shield with Bi
O
/PbO nanoparticles can be cost-effective and cytocompatible with the best antibacterial/antifungal properties.</description><issn>2251-7200</issn><issn>2251-7200</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNqFj81Kw0AUhQdRbNG-gch9gCSdH03qsg0WN9qgLtyVm8lUbklmwsxUzDv5kEZQdOfZnMPH4XIPYxeCZ0rkuZjv695kb5x4Jq-4SkWh8iM2lfJapIXk_PhPnrBZCHs-qhBKFsUpm6ibQuaLBZ-yj9J1PXoKzoLbwUv6iAMsYzT2gJFGWBm_c75Dq00CSxupI-1dTdhC5V1vfCQTEkDbQDlEF907aYrD17Enakk7a9IVBtPAPUZP2gQonY1IluwrrAgkbEBBAlW9ScD5XzQfCTygdeN_kXRrwjk72WEbzOzbz9jl-va5vEv7Q92ZZtt76tAP25956t_CJ8_dY94</recordid><startdate>202412</startdate><enddate>202412</enddate><creator>Divband, Baharak</creator><creator>Haleem Al-Qaim, Zahraa</creator><creator>Hussein, Falah H</creator><creator>Khezerloo, Davood</creator><creator>Gharehaghaji, Nahideh</creator><scope>NPM</scope></search><sort><creationdate>202412</creationdate><title>Comparison of X-Ray Attenuation Performance, Antimicrobial Properties, and Cytotoxicity of Silicone-Based Matrices Containing Bi 2 O 3 , PbO, or Bi 2 O 3 /PbO Nanoparticles</title><author>Divband, Baharak ; Haleem Al-Qaim, Zahraa ; Hussein, Falah H ; Khezerloo, Davood ; Gharehaghaji, Nahideh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_397268803</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Divband, Baharak</creatorcontrib><creatorcontrib>Haleem Al-Qaim, Zahraa</creatorcontrib><creatorcontrib>Hussein, Falah H</creatorcontrib><creatorcontrib>Khezerloo, Davood</creatorcontrib><creatorcontrib>Gharehaghaji, Nahideh</creatorcontrib><collection>PubMed</collection><jtitle>Journal of biomedical physics and engineering</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Divband, Baharak</au><au>Haleem Al-Qaim, Zahraa</au><au>Hussein, Falah H</au><au>Khezerloo, Davood</au><au>Gharehaghaji, Nahideh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of X-Ray Attenuation Performance, Antimicrobial Properties, and Cytotoxicity of Silicone-Based Matrices Containing Bi 2 O 3 , PbO, or Bi 2 O 3 /PbO Nanoparticles</atitle><jtitle>Journal of biomedical physics and engineering</jtitle><addtitle>J Biomed Phys Eng</addtitle><date>2024-12</date><risdate>2024</risdate><volume>14</volume><issue>6</issue><spage>533</spage><pages>533-</pages><issn>2251-7200</issn><eissn>2251-7200</eissn><abstract>Application of the nanomaterials to preparing X-ray shields and successfully treating multiresistant microorganisms has attracted great attention in modern life.
This study aimed to prepare flexible silicone-based matrices containing Bi
O
, PbO, or Bi
O
/PbO nanoparticles and select a cost-effective, cytocompatible, and antibacterial/antifungal X-ray shield in clinical radiography.
In this experimental study, we prepared the nanoparticles by the modified biosynthesis method and fabricated the X-ray shields containing 20 wt% of the nanoparticles. The X-ray attenuation percentage and Half Value Layer (HVL) of the shields were investigated for the photon energies in the range of 40-100 kVp in clinical radiography. The antibacterial/antifungal activities of the shields were evaluated using a colony count method for the gram-negative (
), and gram-positive (
) bacteria, and Candida albicans fungus. The shield toxicity was investigated on A549 cells.
The highest X-ray attenuation percentage and the lowest HVL were obtained using the shield containing Bi
O
nanoparticles. Although all shields displayed antimicrobial activity, the shield containing Bi
O
/PbO nanoparticles showed the most effective reduction in the colony counts. Both X-ray shields containing nano Bi
O
and Bi
O
/PbO demonstrated high cytocompatibility on A549 cells at a concentration as high as 500 µg/ml. The shield with PbO nanoparticles was also cytocompatible at a concentration of 50 µg/ml.
The best X-ray attenuation performance is attributed to the silicone-based matrix with nano Bi
O
; however, the flexible shield with Bi
O
/PbO nanoparticles can be cost-effective and cytocompatible with the best antibacterial/antifungal properties.</abstract><cop>Iran</cop><pmid>39726880</pmid><doi>10.31661/jbpe.v0i0.2403-1736</doi></addata></record> |
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source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
title | Comparison of X-Ray Attenuation Performance, Antimicrobial Properties, and Cytotoxicity of Silicone-Based Matrices Containing Bi 2 O 3 , PbO, or Bi 2 O 3 /PbO Nanoparticles |
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