Steric Hindrance Tuned [4 + 1] Annulation of α-Substituted Conjugated Enones with Ylides for Dihydrofuran Synthesis
In sharp contrast to the intuitive modulation by the electronic effect, the [4 + 1] annulation reaction between α-substituted conjugated enones and ylides has been reliably controlled by the match of the α-substituent and the ylide in steric hindrance, providing a straightforward and efficient metho...
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Veröffentlicht in: | Organic letters 2024-12 |
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Sprache: | eng |
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