The molecular mechanism of Xiaoyaosan in treating major depressive disorder: integrated analysis of DNA methylation and RNA sequencing of the arcuate nucleus in rats

Xiaoyaosan, a classic Chinese herbal formula, exhibits promising antidepressant effects. However, its specific antidepressant mechanisms remain incompletely understood. Previous studies have highlighted the significant role of DNA methylation in the pathogenesis of major depressive disorder (MDD). Y...

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Veröffentlicht in:Journal of ethnopharmacology 2024-12, Vol.340, p.119234, Article 119234
Hauptverfasser: Wang, Rongyanqi, Zou, Tan, Wang, Yidi, Liu, Yueyun, MO, Xiaowei, Chen, Yueyue, Li, Xiaojuan, Chen, Jiaxu
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Sprache:eng
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