Polymethoxyflavones from Gardenia oudiepe and semi-synthetic derivatives reduce nociception in mice: Evidence for the involvement of the MAPK pathway

This study explores the potential of polymethoxyflavones (PMFs) and polyacetylated flavones (PAFs) as novel analgesic and anti-inflammatory agents. Eight derivatives, isolated from Gardenia oudiepe bud exudate or semi-synthesized from commercial kaempferol, underwent evaluations in various in vivo,...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2024-12, Vol.182, p.117742
Hauptverfasser:	Daviaud, Clément, Ferraz, Christiane Adrielly Alves, E Silva, Mariana Gama, de Alencar Filho, Edilson Beserra, Evangelista Mendes de Lima, Sammya Yasmin, Dumontet, Vincent, Júnior, Lucindo José Quintans, da Silva Almeida, Jackson Roberto Guedes, Picot, Laurent, Baranger, Kévin, de Oliveira Júnior, Raimundo Gonçalves, Grougnet, Raphaël
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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